10th Annual ECD Medical Symposium Barcelona, Spain

Barcelona Medical Symposium Group Picture 2025

Symposium Summary

Approximately 54 medical professionals from 8 countries attended the Annual ECD Medical Symposium in 2025.  Eighteen oral abstracts were presented, along with an additional 8 poster presentations.  As an invited speaker, Manel Juan, MD, delivered an invited talk titled “CAR-T-cell Immunoherapies: driving therapies beyond Hematological Cancers, through the Barcelona model.”  An evening reception provided time for discussions supporting current and future collaborations among this highly knowledgeable group of physicians and scientists, all interested in learning more about Erdheim-Chester Disease.

Programs with Symposium Agenda

Agenda

PresenterPresentation Title & SlidesVideo
Xavier Solanich, Paul HendrieWelcome to Barcelona and the 10th Annual Erdheim-Chester Disease International ConferenceWatch (1)

Watch (2)
Manel JuanCAR-T-cell Immunoherapies: driving
therapies beyond Hematological Cancers,
through the Barcelona model.
Watch
Oshrat Hershkovitz-RokahAdvanced proteomic profiling for biomarker discovery in Erdheim-Chester DiseaseWatch
Benjamin DurhamRAF-independent MEK mutations drive refractory histiocytic neoplasms but respond to ERK inhibitionWatch
Julien HarocheBCL-2 immunohistochemistry expression in patients with histiocytosisWatch
Lindsay HillComparative Genetic Analysis of Primary versus Secondary Histiocytic Sarcoma: A Single Institution Case SeriesWatch
Carla Isabel BorreComparative Efficacy of Frontline Targeted Therapies Versus Chemotherapy in MAPK-Pathway Altered Histiocytic NeoplasmsWatch
Francesco PegoraroSecond cancer in Erdheim-Chester diseaseWatch
Jerome RazanamaheryGlomeruloid angioma in Erdheim-Chester disease: an atypical skin manifestation associated with elevated VEGF-AWatch
Francesco CatameròTreatment Holidays in Patients with Erdheim-Chester Disease Receiving Vemurafenib: A Prospective Pilot StudyWatch
Brinda ShuklaDon’t Dish Out Old Therapies: Use of Pegylated-Interferon-Alpha in a case of Erdheim-Chester Disease with congestive heart failure
Watch
Eli DiamondSymptoms, unmet needs, and quality of life in Erdheim-Chester disease: A longitudinal registry-based analysisWatch
Pudis MichalDiagnostic Impact of 18F-FDG PET/MRI over PET/CT in Histiocytoses: A Prospective Comparative StudyWatch
Francesco PegoraroNatural history of Erdheim-Chester disease. A preliminary analysis on 1044 patients within the ECDGA networkWatch
Mia PoleksicErdheim-Chester Disease: Evolving Insights and Improved Survival Over TimeWatch
Gaurav GoyalReal-World Efficacy and Toxicity of MEK Inhibitors in Histiocytic NeoplasmsWatch
Jerome RazanamaheryMAPK-kinase mutations and aortic lesions are associated with the distribution of circulating monocytes in histiocytosisWatch
Abdou Malik Da SilvaDeciphering ALK-positive histiocytosis and mimickers using single cell RNAsequencingWatch
Matthew CollinThe clonal origin and evolution of highrisk multisystem histiocytosis in adultsWatch
Polyzois MakrasMapping Erdheim-Chester Disease in Europe through the Core RegistryWatch
Jerome RazanamaheryLayers of Complexity: ECD Diagnosis and management in the presence of confounding comorbidities Jerome Razanamahery Dijon University Hospital, Dijon, France Closing Remarks & Student AbstractWatch
Diane SchrinerECD Global Alliance into the FutureWatch

Photographs