{"id":68000,"date":"2021-01-23T11:19:35","date_gmt":"2021-01-23T17:19:35","guid":{"rendered":"https:\/\/www.erdheim-chester.org\/%e9%80%9a%e9%81%8e%e6%95%b4%e5%90%88-gwas-%e5%92%8c-omic-%e6%95%b8%e6%93%9a%e6%8e%a2%e7%b4%a2-erdheim-chester-%e7%97%85%e7%9a%84%e9%81%ba%e5%82%b3%e6%99%af%e8%a7%80\/"},"modified":"2025-09-11T09:46:54","modified_gmt":"2025-09-11T14:46:54","slug":"%e9%80%9a%e9%81%8e%e6%95%b4%e5%90%88-gwas-%e5%92%8c-omic-%e6%95%b8%e6%93%9a%e6%8e%a2%e7%b4%a2-erdheim-chester-%e7%97%85%e7%9a%84%e9%81%ba%e5%82%b3%e6%99%af%e8%a7%80","status":"publish","type":"post","link":"https:\/\/www.erdheim-chester.org\/zh-hant\/%e9%80%9a%e9%81%8e%e6%95%b4%e5%90%88-gwas-%e5%92%8c-omic-%e6%95%b8%e6%93%9a%e6%8e%a2%e7%b4%a2-erdheim-chester-%e7%97%85%e7%9a%84%e9%81%ba%e5%82%b3%e6%99%af%e8%a7%80\/","title":{"rendered":"\u901a\u904e\u6574\u5408 GWAS \u548c -omic \u6578\u64da\u63a2\u7d22 Erdheim-Chester \u75c5\u7684\u907a\u50b3\u666f\u89c0"},"content":{"rendered":"[et_pb_section global_module=\"47647\"][\/et_pb_section]\n<h4><strong>\u6388\u4e88\u5e74\u4efd\uff1a<\/strong> 2021<br \/>\n<strong>\u91d1\u984d\uff1a<\/strong> 50,000 \u7f8e\u5143<\/h4>\n<p>ECD\u806f\u76df\u5411\u7fa9\u5927\u5229\u4f5b\u7f85\u502b\u85a9\u9081\u8036\u5927\u5b78\u5152\u7ae5\u91ab\u9662\u7684Francesco Pegoraro\u535a\u58eb\u9812\u767c\u4e862021\u5e74ECD\u7814\u7a76\u8cc7\u52a9\u3002\u7372\u52dd\u63d0\u6848 <a href=\"https:\/\/www.erdheim-chester.org\/wp-content\/uploads\/2022\/01\/2022.01-F.-Pegoraro-Grant-PR.pdf\" target=\"_blank\" rel=\"noopener\" aria-label=\"Exploring the genetic landscape of Erdheim-Chester disease by integrating GWAS and -omic data - opens in new tab - opens in new tab\">Exploring the genetic landscape of Erdheim-Chester disease by integrating GWAS and -omic data<\/a>\uff0c\u88ab\u9078\u4e2d\u7372\u5f97 50,000 \u7f8e\u5143\u7684\u8cc7\u52a9\u3002ECDGA \u5f88\u69ae\u5e78\u80fd\u5920\u8cc7\u52a9\u9019\u9805\u958b\u5275\u6027\u7684\u5de5\u4f5c\uff0c\u4e26\u76f8\u4fe1\u9019\u5c07\u70ba ECD \u60a3\u8005\u5e36\u4f86\u66f4\u5149\u660e\u7684\u672a\u4f86\uff0c\u4e26\u66f4\u597d\u5730\u4e86\u89e3\u7d44\u7e54\u7d30\u80de\u589e\u591a\u75c7\u3002\u67e5\u770b\u65b0\u805e\u7a3f   <\/p>\n<h3><strong>\u4e2d\u671f\u5831\u544a<\/strong><\/h3>\n<p>\u984c\u70ba\u300c\u901a\u904e\u6574\u5408 GWAS \u548c -omic \u6578\u64da\u63a2\u7d22 Erdheim-Chester \u75c5\u7684\u907a\u50b3\u666f\u89c0\u300d\u7684\u5c08\u6848\u65e8\u5728\u901a\u904e\u9032\u884c\u7532\u57fa\u5316\u548c\u57fa\u56e0\u8868\u9054\u7814\u7a76\u4f86\u7814\u7a76 ECD \u7684\u907a\u50b3\u6613\u611f\u6027\u3002ECD \u7684\u5168\u57fa\u56e0\u7d44\u95dc\u806f\u7814\u7a76\u7d50\u679c\u5df2\u5728 2023 \u5e74 ECDGA \u6703\u8b70\u4e0a\u516c\u4f48\uff0c\u76ee\u524d\u6b63\u5728\u63d0\u4ea4\u767c\u8868\uff0c\u8a72\u7814\u7a76\u78ba\u5b9a\u4e86\u8207 ECD \u6613\u611f\u6027\u76f8\u95dc\u7684\u907a\u50b3\u8b8a\u7570 \uff08SETBP1\uff09\u3002\u6211\u5011\u73fe\u5728\u6b63\u5728\u5206\u6790\u60a3\u8005\u7684\u7532\u57fa\u5316\u7d44\u548c\u57fa\u56e0\u8868\u9054\uff0c\u4ee5\u66f4\u597d\u5730\u77ad\u89e3SETBP1 \u5728\u75be\u75c5\u767c\u75c5\u6a5f\u5236\u4e2d\u7684\u4f5c\u7528\u3002\u5c07\u5c0dECD\u4e2d\u6700\u91cd\u8981\u7684\u7d30\u80de\u985e\u578b\uff08\u55ae\u6838\u7d30\u80de\uff09\u9032\u884c\u76f8\u540c\u7684\u5206\u6790\uff0c\u70ba\u4e86\u5b8c\u6210\u9019\u9805\u4efb\u52d9\uff0c\u6211\u5011\u76ee\u524d\u6b63\u5728\u5c0dECD\u60a3\u8005\u9032\u884c\u63a1\u6a23\u548c\u55ae\u6838\u7d30\u80de\u63d0\u53d6\u3002\u7136\u5f8c\uff0c\u9019\u4e9b\u6a23\u672c\u5c07\u88ab\u904b\u9001\u5230 Martin \u6559\u6388\u7684\u5be6\u9a57\u5ba4\uff0c\u5728\u90a3\u88e1\u9032\u884c\u57fa\u56e0\u5206\u6790\u3002    <\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4f86\u81ea\u7fa9\u5927\u5229\u4f5b\u7f85\u502b\u85a9\u9081\u8036\u5927\u5b78\u5152\u7ae5\u91ab\u9662\u7684Francesco Pegoraro\u535a\u58eb\u7372\u5f97\u4e8650,000\u7f8e\u5143\u7684ECD\u5168\u7403\u806f\u76df\u8cc7\u52a9\uff0c\u7528\u65bc\u63a2\u7d22 Erdheim-Chester \u75c5\u7684\u907a\u50b3\u666f\u89c0\u3002\u9019\u9805\u958b\u5275\u6027\u7684\u7814\u7a76\u78ba\u5b9a\u4e86\u4e00\u7a2e\u8207 ECD \u6613\u611f\u6027\u76f8\u95dc\u7684\u907a\u50b3\u8b8a\u7570 \uff08SETBP1\uff09\uff0c\u4e26\u901a\u904e\u5168\u9762\u7684\u907a\u50b3\u548c\u5206\u5b50\u5206\u6790\u7e7c\u7e8c\u7814\u7a76\u5176\u5728\u75be\u75c5\u767c\u75c5\u6a5f\u5236\u4e2d\u7684\u4f5c\u7528\u3002 <\/p>\n","protected":false},"author":20,"featured_media":92334,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","_wds_title":"","_wds_metadesc":"","_wds_focus-keywords":"","_wds_meta-robots-adv":"","_wds_meta-robots-noindex":false,"_wds_meta-robots-nofollow":false,"_wds_meta-robots-index":false,"_wds_meta-robots-follow":false,"_wds_autolinks-exclude":false,"_wds_canonical":"","_wds_redirect":"","_wds_opengraph":[],"_wds_twitter":[],"cybocfi_hide_featured_image":"","wds_primary_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[604],"tags":[668],"class_list":["post-68000","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-604","tag-2021-zh-hant"],"_links":{"self":[{"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/posts\/68000","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/comments?post=68000"}],"version-history":[{"count":0,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/posts\/68000\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/media\/92334"}],"wp:attachment":[{"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/media?parent=68000"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/categories?post=68000"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/tags?post=68000"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}