{"id":54912,"date":"2025-04-29T05:26:50","date_gmt":"2025-04-29T09:26:50","guid":{"rendered":"https:\/\/www.erdheim-chester.org\/msk-%e6%96%af%e9%9a%86%e7%a0%94%e7%a9%b6%e4%ba%ae%e9%bb%9e%ef%bc%9a%e7%bd%95%e8%a6%8b%e7%99%8c%e7%97%87%e7%a0%94%e7%a9%b6%e9%80%b2%e5%b1%95\/"},"modified":"2025-08-23T17:32:18","modified_gmt":"2025-08-23T21:32:18","slug":"msk-%e6%96%af%e9%9a%86%e7%a0%94%e7%a9%b6%e4%ba%ae%e9%bb%9e%ef%bc%9a%e7%bd%95%e8%a6%8b%e7%99%8c%e7%97%87%e7%a0%94%e7%a9%b6%e9%80%b2%e5%b1%95","status":"publish","type":"post","link":"https:\/\/www.erdheim-chester.org\/zh-hant\/msk-%e6%96%af%e9%9a%86%e7%a0%94%e7%a9%b6%e4%ba%ae%e9%bb%9e%ef%bc%9a%e7%bd%95%e8%a6%8b%e7%99%8c%e7%97%87%e7%a0%94%e7%a9%b6%e9%80%b2%e5%b1%95\/","title":{"rendered":"MSK \u65af\u9686\u7814\u7a76\u4eae\u9ede\uff1a\u7f55\u898b\u764c\u75c7\u7814\u7a76\u9032\u5c55"},"content":{"rendered":"<h2>\u5be6\u9a57\u5ba4\u4e2d\u7684\u5e0c\u671b\uff1aMSK \u65af\u9686\u7814\u7a76\u63ed\u793a\u4e86 ECD \u548c\u5927\u8166<\/h2>\n<p>2025 \u5e74 3 \u6708 26 \u65e5\uff0c <em>\u7d00\u5ff5\u65af\u9686\u51f1\u7279\u7433\u764c\u75c7\u4e2d\u5fc3 \uff08MSK\uff09 \u7814\u7a76\u4eae\u9ede<\/em> \u4e2d\u65b0\u767c\u8868\u7684\u4e00\u9805\u7814\u7a76\u70ba\u5384 Erdheim-Chester \u75c5 \uff08ECD\uff09 \u548c\u985e\u4f3c\u7684\u7d44\u7e54\u7d30\u80de\u75be\u75c5\u5982\u4f55\u5f71\u97ff\u5927\u8166\u63d0\u4f9b\u4e86\u91cd\u8981\u898b\u89e3\u3002\u9019\u9805\u7814\u7a76\u5e36\u4f86\u4e86\u4e00\u500b\u5e0c\u671b\u7684\u8cc7\u8a0a\uff1a\u6b63\u5728\u7a4d\u6975\u9032\u884c\u57fa\u790e\u79d1\u5b78\u7814\u7a76\uff0c\u4ee5\u77ad\u89e3 ECD \u7684\u6f5b\u5728\u751f\u7269\u5b78\u7279\u6027\uff0c\u800c\u9019\u4e9b\u77e5\u8b58\u53ef\u4ee5\u5e6b\u52a9\u5728\u640d\u5bb3\u8b8a\u5f97\u4e0d\u53ef\u9006\u8f49\u4e4b\u524d\u9632\u6b62\u640d\u5bb3\u3002 <\/p>\n<p>\u9019\u7bc7\u767c\u8868\u5728\u300a<em>\u795e\u7d93\u5143<\/em>\u300b\u96dc\u8a8c\u4e0a\u7684\u7814\u7a76\u8ad6\u6587\u5305\u62ec\u5e7e\u4f4d\u7a4d\u6781\u53c3\u8207\u7814\u7a76 Erdheim-Chester \u75c5\u7684\u4f5c\u8005\u3002\u5176\u4e2d\u5305\u62ec <b>Julien Haroche \u535a\u58eb<\/b>\uff08\u5df4\u9ece H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re\uff09\u548c <b>Eli Diamond \u535a\u58eb\uff08MSK\uff09\uff0c<\/b>\u4ed6\u5011\u90fd\u662f\u9818\u5148\u7684\u81e8\u5e8a\u79d1\u5b78\u5bb6\uff0c\u4ee5\u81f4\u529b\u65bc ECD \u7814\u7a76\u548c\u8b77\u7406\u800c\u805e\u540d\u3002\u9019\u9805\u5de5\u4f5c\u9084\u6d89\u53ca<strong>\u5176\u4ed6\u6b63\u5728\u7814\u7a76 ECD \u7684\u79d1\u5b78\u5bb6<\/strong>\uff0c\u9019\u53cd\u6620\u4e86\u5168\u7403\u70ba\u5728\u7d30\u80de\u6c34\u5e73\u4e0a\u77ad\u89e3\u9019\u7a2e\u7f55\u898b\u75be\u75c5\u800c\u4e0d\u65b7\u589e\u5f37\u7684\u5408\u4f5c\u52aa\u529b\u3002  <\/p>\n<p>\u9019\u9805\u7814\u7a76\u7684\u91cd\u9ede\u662f\u7279\u5b9a\u7684\u57fa\u56e0\u7a81\u8b8a\uff08\u5c24\u5176\u662f <strong>MAPK \u901a\u8def<\/strong>\u4e2d\u7684\u57fa\u56e0\u7a81\u8b8a\uff0c\u4f8b\u5982 <strong>BRAFV600E<\/strong> \u7a81\u8b8a\uff09\u5982\u4f55\u6539\u8b8a\u514d\u75ab\u7d30\u80de\u7684\u884c\u70ba\u3002\u9019\u4e9b\u8b8a\u5316\u53ef\u80fd\u6703\u5f15\u8d77\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71 \uff08CNS\uff09 \u7684\u708e\u75c7\u548c\u640d\u50b7\u3002\u9019\u4e9b\u767c\u73fe\u5f37\u5316\u4e86\u60a3\u8005\u548c\u91ab\u751f\u9577\u671f\u4ee5\u4f86\u89c0\u5bdf\u5230\u7684\u4e8b\u5be6\uff1a ECD \u6703\u7522\u751f\u795e\u7d93\u7cfb\u7d71\u5f71\u97ff\uff0c\u5305\u62ec\u5e73\u8861\u554f\u984c\u3001\u8a18\u61b6\u554f\u984c\u548c\u8377\u723e\u8499\u5931\u8861\u3002\u91cd\u8981\u7684\u662f\uff0c\u7814\u7a76\u8868\u660e\uff0c\u9019\u4e9b\u5927\u8166\u8b8a\u5316\u53ef\u80fd\u5728\u7665\u72c0\u51fa\u73fe\u4e4b\u524d\u5f88\u4e45\u5c31\u958b\u59cb\u4e86\u2014\u2014\u9019\u6253\u958b\u4e86\u4e00\u500b <em>\u6cbb\u7642\u8996\u7a97<\/em> \uff0c\u65e9\u671f\u5e72\u9810\u53ef\u80fd\u6703\u9632\u6b62\u9577\u671f\u50b7\u5bb3\u3002   <\/p>\n<blockquote><p>\u201c\u96a8\u8457\u77ad\u89e3\u7684\u6df1\u5165\uff0c\u6f2b\u9577\u7684\u81e8\u5e8a\u524d\u968e\u6bb5\u4f3c\u4e4e\u4ee3\u8868\u4e86\u5728\u9020\u6210\u4e0d\u53ef\u9006\u640d\u5bb3\u4e4b\u524d\u7684\u6cbb\u7642\u8996\u7a97\u3002\u201d<\/p><\/blockquote>\n<p>\u9019\u9805\u5de5\u4f5c\u6280\u8853\u6027\u5f88\u5f37\uff0c\u4f46\u5176\u5f71\u97ff\u662f\u660e\u78ba\u7684\uff1a\u5728\u5206\u5b50\u6c34\u6e96\u4e0a\u66f4\u6df1\u5165\u5730\u77ad\u89e3 ECD \u5c07\u5c0e\u81f4\u66f4\u597d\u7684\u8a3a\u65b7\u3001\u66f4\u65e9\u7684\u6aa2\u6e2c\uff0c\u4e26\u6709\u671b\u5728\u672a\u4f86\u63d0\u4f9b\u66f4\u6709\u6548\u7684\u6cbb\u7642\u65b9\u6cd5\u3002<\/p>\n<p>\u95b1\u8b80 <em>Neuron<\/em> \u4e0a<strong>\u7684\u5b8c\u6574\u79d1\u5b78\u6587\u7ae0<\/strong>\uff08\u6ce8\uff1a\u6280\u8853\u5167\u5bb9\uff09\uff1a<br \/>\n<a href=\"https:\/\/www.cell.com\/action\/showPdf?pii=S0896-6273%2825%2900120-5\" target=\"_blank\" rel=\"noopener\" aria-label=\"https:\/\/www.cell.com\/action\/showPdf?pii=S0896-6273%2825%2900120-5 - opens in new tab\">https:\/\/www.cell.com\/action\/showPdf?pii=S0896-6273%2825%2900120-5<\/a><\/p>\n<p><strong>\u95b1\u8b80 MSK \u65b0\u805e\u6458\u8981<\/strong>\uff1a<br \/>\n<a href=\"https:\/\/www.mskcc.org\/news\/msk-research-highlights-march-26-2025\" target=\"_blank\" rel=\"noopener\" aria-label=\"MSK Research Highlights \u2013 March 26, 2025 - opens in new tab\">MSK \u65af\u9686\u7814\u7a76\u4eae\u9ede \u2013 2025 \u5e74 3 \u6708 26 \u65e5<\/a><\/p>\n<p>\u4f5c\u70ba\u4e00\u500b\u81f4\u529b\u65bc\u652f\u63f4\u7814\u7a76\u3001\u6559\u80b2\u548c\u610f\u8b58\u7684\u7d44\u7e54\uff0cECD \u5168\u7403\u806f\u76df\u8b9a\u63da\u9019\u652f\u656c\u696d\u7684\u79d1\u5b78\u5bb6\u5718\u968a\u7e7c\u7e8c\u63ed\u958b Erdheim-Chester \u75c5\u7684\u795e\u79d8\u9762\u7d17\u3002\u6bcf\u4e00\u9805\u767c\u73fe\u90fd\u4f7f\u6211\u5011\u96e2\u6539\u5584\u53d7\u5f71\u97ff\u8005\u7684\u7d50\u679c\u548c\u751f\u6d3b\u54c1\u8cea\u66f4\u8fd1\u4e86\u4e00\u6b65\u3002 <\/p>\n<hr>\n<p><em>Erdheim-Chester \u75c5\u5168\u7403\u806f\u76df \uff08ECDGA \u4e0d\u63d0\u4f9b\u91ab\u7642\u5efa\u8b70\u3001\u8a3a\u65b7\u6216\u6cbb\u7642\u3002\u6240\u6709\u5167\u5bb9\u50c5\u4f9b\u53c3\u8003\u3002\u5982\u6709\u91ab\u7642\u554f\u984c\uff0c\u8acb\u8aee\u8a62\u91ab\u7642\u4fdd\u5065\u63d0\u4f9b\u8005\u3002  <\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5be6\u9a57\u5ba4\u4e2d\u7684\u5e0c\u671b\uff1aMSK \u65af\u9686\u7814\u7a76\u63ed\u793a\u4e86 ECD \u548c\u5927\u8166 20 [&hellip;]<\/p>\n","protected":false},"author":20,"featured_media":48299,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","_wds_title":"","_wds_metadesc":"","_wds_focus-keywords":"","_wds_meta-robots-adv":"","_wds_meta-robots-noindex":false,"_wds_meta-robots-nofollow":false,"_wds_meta-robots-index":false,"_wds_meta-robots-follow":false,"_wds_autolinks-exclude":false,"_wds_canonical":"","_wds_redirect":"","_wds_opengraph":[],"_wds_twitter":[],"cybocfi_hide_featured_image":"","wds_primary_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[422],"tags":[],"class_list":["post-54912","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ecdga-"],"_links":{"self":[{"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/posts\/54912","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/comments?post=54912"}],"version-history":[{"count":0,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/posts\/54912\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/media\/48299"}],"wp:attachment":[{"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/media?parent=54912"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/categories?post=54912"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/tags?post=54912"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}