{"id":107530,"date":"2025-11-13T10:27:57","date_gmt":"2025-11-13T16:27:57","guid":{"rendered":"https:\/\/www.erdheim-chester.org\/%e4%ba%86%e8%a7%a3%e5%9f%83%e7%88%be%e5%be%b7%e6%b5%b7%e5%a7%86-%e5%88%87%e6%96%af%e7%89%b9%e7%97%85%ef%bc%9a%e5%88%86%e5%ad%90%e5%92%8c%e8%87%a8%e5%ba%8a%e5%89%8d%e6%99%af\/"},"modified":"2025-11-13T18:40:02","modified_gmt":"2025-11-14T00:40:02","slug":"%e4%ba%86%e8%a7%a3%e5%9f%83%e7%88%be%e5%be%b7%e6%b5%b7%e5%a7%86-%e5%88%87%e6%96%af%e7%89%b9%e7%97%85%ef%bc%9a%e5%88%86%e5%ad%90%e5%92%8c%e8%87%a8%e5%ba%8a%e5%89%8d%e6%99%af","status":"publish","type":"post","link":"https:\/\/www.erdheim-chester.org\/zh-hant\/%e4%ba%86%e8%a7%a3%e5%9f%83%e7%88%be%e5%be%b7%e6%b5%b7%e5%a7%86-%e5%88%87%e6%96%af%e7%89%b9%e7%97%85%ef%bc%9a%e5%88%86%e5%ad%90%e5%92%8c%e8%87%a8%e5%ba%8a%e5%89%8d%e6%99%af\/","title":{"rendered":"\u4e86\u89e3\u57c3\u723e\u5fb7\u6d77\u59c6-\u5207\u65af\u7279\u75c5\uff1a\u5206\u5b50\u548c\u81e8\u5e8a\u524d\u666f"},"content":{"rendered":"<p><iframe loading=\"lazy\" title=\"Understanding Erdheim-Chester Disease: The Molecular and Clinical Landscape\" width=\"1080\" height=\"608\" src=\"https:\/\/www.youtube.com\/embed\/rlS4IVA50rI?feature=oembed\"  allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p>\u7531\u8840\u6db2\u816b\u7624\u5b78\u5bb6 Sam Reynolds \u535a\u58eb\u8207\u57c3\u5fb7\u6d77\u59c6-\u5207\u65af\u7279\u75c5\u5168\u7403\u806f\u76df \uff08ECDGA\uff09 \u5408\u4f5c\u4e3b\u6301\u3002\u672c\u6f14\u8b1b\u63a2\u8a0e\u4e86\u57c3\u5fb7\u6d77\u59c6-\u5207\u65af\u7279\u75c5 \uff08ECD\uff09 \u7684\u5206\u5b50\u548c\u81e8\u5e8a\u8907\u96dc\u6027\uff0c\u9019\u662f\u4e00\u7a2e\u7f55\u898b\u7684\u7d44\u7e54\u7d30\u80de\u75be\u75c5\uff0c\u5176\u7279\u5fb5\u662f\u7a31\u70ba\u7d44\u7e54\u7d30\u80de\u7684\u7570\u5e38\u514d\u75ab\u7d30\u80de\u904e\u5ea6\u7522\u751f\u3002\u96f7\u8afe\u8332\u535a\u58eb\u5229\u7528\u5bc6\u897f\u6839\u5927\u5b78\u3001\u6885\u5967\u8a3a\u6240\u3001\u9054\u7d0d\u6cd5\u4f2f\u548c\u963f\u62c9\u5df4\u99ac\u5927\u5b78\u4f2f\u660e\u7ff0\u5206\u6821\u7b49\u4e3b\u8981\u91ab\u7642\u4e2d\u5fc3\u7684\u7814\u7a76\u5408\u4f5c\uff0c\u5168\u9762\u6982\u8ff0\u4e86 ECD \u7684\u8d77\u6e90\u3001\u8b8a\u7570\u6027\u548c\u65b0\u8208\u7814\u7a76\u65b9\u5411\u3002  <\/p>\n<p>\u900f\u904e\u6e05\u6670\u7684\u8996\u89ba\u6548\u679c\u548c\u6848\u4f8b\uff0c\u96f7\u8afe\u8332\u535a\u58eb\u89e3\u91cb\u4e86 ECD \u5982\u4f55\u7531\u55ae\u6838\u7d30\u80de\u7a81\u8b8a\u767c\u5c55\u800c\u4f86\uff0c\u55ae\u6838\u7d30\u80de\u662f\u53ef\u4ee5\u5728\u7d44\u7e54\u5167\u8f49\u5316\u70ba\u7d44\u7e54\u7d30\u80de\u7684\u7279\u6b8a\u767d\u8840\u7403\u3002\u4ed6\u8aaa\u660e\u4e86\u9019\u4e9b\u7a81\u8b8a\u901a\u5e38\u5728 MAPK \u9014\u5f91\uff08\u5305\u62ec BRAF\u3001KRAS \u548c MAP2K1\uff09\u5167\u5982\u4f55\u7834\u58de\u6b63\u5e38\u7d30\u80de\u751f\u9577\u4e26\u5c0e\u81f4\u708e\u75c7\u3001\u7e96\u7dad\u5316\u548c\u7d44\u7e54\u640d\u50b7\u3002\u8a0e\u8ad6\u9084\u63a2\u8a0e\u4e86\u9019\u4e9b\u907a\u50b3\u5b78\u767c\u73fe\u5982\u4f55\u63a8\u52d5\u7cbe\u6e96\u816b\u7624\u5b78\u7684\u8208\u8d77\u2014\u2014\u6839\u64da\u60a3\u8005\u7684\u7279\u5b9a\u5206\u5b50\u8b5c\u9032\u884c\u91dd\u5c0d\u6027\u7684\u6cbb\u7642\u3002  <\/p>\n<p>\u672c\u6b21\u7db2\u8def\u7814\u8a0e\u6703\u6db5\u84cb\u7684\u4e3b\u8981\u4e3b\u984c\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>ECD \u5982\u4f55\u7531\u55ae\u6838\u7d30\u80de\u548c\u7d44\u7e54\u7d30\u80de\u7684\u7570\u5e38\u5f15\u8d77<\/li>\n<li>\u9ad4\u7d30\u80de\u7a81\u8b8a\u5728\u75be\u75c5\u9032\u5c55\u4e2d\u7684\u4f5c\u7528<\/li>\n<li>\u81e8\u5e8a\u7570\u8cea\u6027\uff1a\u70ba\u4ec0\u9ebc\u6c92\u6709\u5169\u500b ECD \u60a3\u8005\u662f\u76f8\u540c\u7684<\/li>\n<li>\u6a19\u9776\u6cbb\u7642\u548c\u7cbe\u6e96\u91ab\u5b78\u7684\u9032\u5c55<\/li>\n<li>ECD\u3001\u514b\u9686\u9020\u8840\u548c\u7e7c\u767c\u6027\u764c\u75c7\uff08\u5982AML\uff09\u4e4b\u9593\u7684\u806f\u7e6b<\/li>\n<li>\u6301\u7e8c\u7814\u7a76\u548c\u60a3\u8005\u5408\u4f5c\u7684\u91cd\u8981\u6027<\/li>\n<\/ul>\n<p>\u96f7\u8afe\u8332\u535a\u58eb\u5f37\u8abf\uff0c\u4e86\u89e3 ECD \u7684\u5206\u5b50\u666f\u89c0\u4e0d\u50c5\u53ef\u4ee5\u52a0\u6df1\u79d1\u5b78\u77e5\u8b58\uff0c\u9084\u53ef\u4ee5\u63d0\u9ad8\u500b\u4eba\u5316\u6cbb\u7642\u3001\u9810\u6e2c\u7d50\u679c\u548c\u63d0\u9ad8\u751f\u6d3b\u54c1\u8cea\u7684\u80fd\u529b\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7531\u8840\u6db2\u816b\u7624\u5b78\u5bb6 Sam Reynolds \u535a\u58eb\u8207\u57c3\u5fb7\u6d77\u59c6-\u5207\u65af\u7279\u75c5\u5168\u7403\u806f\u76df \uff08ECDGA\uff09 \u5408\u4f5c\u4e3b\u6301\u3002\u672c\u6f14\u8b1b\u63a2\u8a0e\u4e86\u57c3\u5fb7\u6d77\u59c6-\u5207\u65af\u7279\u75c5 \uff08ECD\uff09 \u7684\u5206\u5b50\u548c\u81e8\u5e8a\u8907\u96dc\u6027\uff0c\u9019\u662f\u4e00\u7a2e\u7f55\u898b\u7684\u7d44\u7e54\u7d30\u80de\u75be\u75c5\uff0c\u5176\u7279\u5fb5\u662f\u7a31\u70ba\u7d44\u7e54\u7d30\u80de\u7684\u7570\u5e38\u514d\u75ab\u7d30\u80de\u904e\u5ea6\u7522\u751f\u3002 <\/p>\n","protected":false},"author":20,"featured_media":113546,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","_wds_title":"","_wds_metadesc":"","_wds_focus-keywords":"","_wds_meta-robots-adv":"","_wds_meta-robots-noindex":false,"_wds_meta-robots-nofollow":false,"_wds_meta-robots-index":false,"_wds_meta-robots-follow":false,"_wds_autolinks-exclude":false,"_wds_canonical":"","_wds_redirect":"","_wds_opengraph":[],"_wds_twitter":[],"cybocfi_hide_featured_image":"","wds_primary_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[599],"tags":[5455,5450,5459,5068,5448,5456,5449,5452,5451,5454,5073,5453,5069,5458,5457],"class_list":["post-107530","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-599","tag-braf","tag-ecd-","tag-mapk","tag-5448","tag-5456","tag-5449","tag-5452","tag-5451","tag-5454","tag-5073","tag-5453","tag-5069","tag-5458","tag-5457"],"_links":{"self":[{"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/posts\/107530","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/comments?post=107530"}],"version-history":[{"count":0,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/posts\/107530\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/media\/113546"}],"wp:attachment":[{"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/media?parent=107530"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/categories?post=107530"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/zh-hant\/wp-json\/wp\/v2\/tags?post=107530"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}