{"id":102084,"date":"2016-04-01T18:13:58","date_gmt":"2016-04-01T23:13:58","guid":{"rendered":"https:\/\/www.erdheim-chester.org\/4e-jaarlijkse-ecd-medical-symposium-parijs-frankrijk\/"},"modified":"2026-06-12T09:29:37","modified_gmt":"2026-06-12T14:29:37","slug":"4e-jaarlijkse-ecd-medical-symposium-parijs-frankrijk","status":"publish","type":"post","link":"https:\/\/www.erdheim-chester.org\/nl\/4e-jaarlijkse-ecd-medical-symposium-parijs-frankrijk\/","title":{"rendered":"4e jaarlijkse ECD Medical Symposium Parijs, Frankrijk"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.27.6″ _module_preset=”default” custom_padding=”20px||0px||false|false” locked=”off” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row _builder_version=”4.27.6″ _module_preset=”default” width=”65%” width_tablet=”80%” width_phone=”80%” width_last_edited=”on|phone” custom_padding=”||10px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.27.5″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_heading title=”4e jaarlijkse ECD Medical Symposium Parijs, Frankrijk” _builder_version=”4.27.6″ _module_preset=”default” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row module_class=”single-line-buttons ” _builder_version=”4.27.6″ _module_preset=”default” width=”65%” width_tablet=”80%” width_phone=”80%” width_last_edited=”on|phone” custom_padding=”0px||0px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.27.6″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_button button_text=”Xavier Solanich, MD, PHD” _builder_version=”4.27.6″ _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#000000″ button_bg_color=”RGBA(255,255,255,0)” button_border_radius=”0px” button_icon=”||fa||400″ button_icon_color=”#35A4BB” button_icon_placement=”left” button_on_hover=”off” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_button][et_pb_button button_text=”Boulevard de l'H\u00f4pital” _builder_version=”4.27.6″ _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#000000″ button_bg_color=”RGBA(255,255,255,0)” button_border_radius=”0px” button_icon=”||fa||900″ button_icon_color=”#35A4BB” button_icon_placement=”left” button_on_hover=”off” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_button][et_pb_button button_text=”Parijs, Frankrijk” _builder_version=”4.27.6″ _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#000000″ button_bg_color=”RGBA(255,255,255,0)” button_border_radius=”0px” button_icon=”||divi||400″ button_icon_color=”#35A4BB” button_icon_placement=”left” button_on_hover=”off” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_button][et_pb_button button_text=”1 april 2016″ _builder_version=”4.27.6″ _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#000000″ button_bg_color=”RGBA(255,255,255,0)” button_border_radius=”0px” button_icon=”||fa||400″ button_icon_color=”#35A4BB” button_icon_placement=”left” button_on_hover=”off” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.6″ _module_preset=”default” width=”65%” width_tablet=”80%” width_phone=”80%” width_last_edited=”on|phone” custom_padding=”0px||||false|false” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.27.5″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_image src=”https:\/\/www.erdheim-chester.org\/wp-content\/uploads\/2016\/11\/2016-Medical-Symposium-Group-Photo-Small.jpg” title_text=”2016-medisch-symposium-groepsfoto-klein” align=”center” force_fullwidth=”on” module_class=”event-image” _builder_version=”4.27.6″ _module_preset=”default” border_radii=”on|10px|10px|10px|10px” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_image][et_pb_text _builder_version=”4.27.6″ _module_preset=”default” text_font_size=”14px” text_line_height=”-0.1em” text_orientation=”center” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

\n
\n

Groepsfoto Medisch Symposium Parijs 2016<\/p>\n<\/div>\n<\/div>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.27.5″ _module_preset=”default” custom_padding=”0px||||false|false” locked=”off” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row _builder_version=”4.27.6″ _module_preset=”default” width=”65%” width_tablet=”80%” width_phone=”80%” width_last_edited=”on|phone” custom_padding=”10px||||false|false” global_colors_info=”{}” width__hover_enabled=”off|desktop” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.27.5″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.27.6″ _module_preset=”default” custom_margin=”||15px||false|false” border_width_bottom=”2px” border_color_bottom=”#35A4BB” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Samenvatting symposium<\/h2>\n

[\/et_pb_text][et_pb_text _builder_version=”4.27.6″ _module_preset=”default” locked=”off” global_colors_info=”{}” theme_builder_area=”post_content”]De Erdheim-Chester Disease Global Alliance is verheugd u de volgende samenvatting te kunnen aanbieden van de presentaties die zijn gegeven tijdens het 4e jaarlijkse International ECD Medical Symposium, dat op 15 september 2016 plaatsvond in het H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re in Parijs, Frankrijk. De bijeenkomst stelde medische professionals in staat om samen te werken aan ECD-onderzoek, medische bevindingen te delen en de pati\u00ebntenzorg te bespreken. Onze dank gaat uit naar de mede-gastheer van dit jaar, professor Julien Haroche, MD, PhD; naar alle sprekers die hun gegevens en expertise deelden tijdens de paneldiscussies; naar alle aanwezigen die ge\u00efnteresseerd waren om meer te leren over ECD; en naar iedereen die betrokken was bij de planning en het tot een succes maken van dit evenement. Een speciale dank gaat uit naar de vrijwilligers die deze samenvatting hebben opgesteld voor de gemeenschap en voor de professionals die niet aanwezig konden zijn.[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.6″ _module_preset=”default” width=”65%” width_tablet=”80%” width_phone=”80%” width_last_edited=”on|phone” custom_padding=”0px||0px||false|false” locked=”off” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.27.5″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.27.5″ _module_preset=”default” custom_margin=”||15px||false|false” border_width_bottom=”2px” border_color_bottom=”#14b8a6″ global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Programma’s met symposiumagenda<\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row module_class=”single-line-buttons ” _builder_version=”4.27.6″ _module_preset=”default” width=”65%” width_tablet=”80%” width_phone=”80%” width_last_edited=”on|phone” custom_padding=”||0px||false|false” locked=”off” global_colors_info=”{}” column_structure=”1_3,1_3,1_3″ theme_builder_area=”post_content”][et_pb_column type=”1_3″ _builder_version=”4.27.6″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_image src=”https:\/\/www.erdheim-chester.org\/wp-content\/uploads\/2026\/06\/2016-Paris-MS-Program-Cover.jpg” title_text=”Omslag programma MS-symposium Parijs 2016″ url=”https:\/\/www.erdheim-chester.org\/wp-content\/uploads\/2026\/06\/2016-MS-Program.pdf” url_new_window=”on” _builder_version=”4.27.6″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”post_content” sticky_enabled=”0″ border_radii=”on|8px|8px|8px|8px” border_width_all=”1px” border_color_all=”#c6c6c6″][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.27.6″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.27.6″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.6″ _module_preset=”default” width=”65%” width_tablet=”80%” width_phone=”80%” width_last_edited=”on|phone” custom_padding=”||0px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.27.5″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.27.6″ _module_preset=”default” custom_margin=”||15px||false|false” border_width_bottom=”2px” border_color_bottom=”#35A4BB” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Presentaties<\/h2>\n

[\/et_pb_text][et_pb_text _builder_version=”4.27.6″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

De volgende presentaties werden gegeven tijdens de bijeenkomst van 2016. Bezoek het YouTube-kanaal van de ECD Global Alliance<\/a> voor alle gepubliceerde ECD-gerelateerde video’s<\/a>. <\/p>\n

[\/et_pb_text][et_pb_text module_class=”event-table” _builder_version=”4.27.6″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t
Presenter<\/th>Presentation Slides<\/th>Videos<\/th>\n<\/tr>\n<\/thead>\n
Prof. Julien Haroche, MD, PhD<\/td>Welcome<\/td>Welcome<\/a><\/td>\n<\/tr>\n
Omar Abdel-Wahab, MD, PhD and Benjamin Durham, MD;<\/td>Insights into the Cell-of-Origin of the Histiocytoses Using Patient-\u00ad\u2010Derived Xenograft Murine Models<\/a><\/td>Insights into the Cell-of-Origin of the Histiocytoses Using Patient-\u00ad\u2010Derived Xenograft Murine Models<\/a><\/td>\n<\/tr>\n
Lorenzo Dagna, MD, PhD<\/td>CCL18 in Erdheim-Chester Disease: Potential Implications in the Pathogenesis<\/td>Not available<\/td>\n<\/tr>\n
Matthew Collin, MD<\/td>The Hematopoietic Origin of Adult Histiocytosis<\/td>Not available<\/td>\n<\/tr>\n
Matthias Papo, MD<\/td>Erdheim-Chester disease is frequently associated with myeloproliferative neoplasms and myelodysplastic syndromes: a systematic clinical and molecular series of 189 patients<\/td>Not available<\/td>\n<\/tr>\n
Fleur Cohen-Aubart, MD & Wilfred Le Goff, MD<\/td>Marked alteration of circulating immune cells in Erdheim-Chester disease in a large single-center series of 46 patients<\/td>Not available<\/td>\n<\/tr>\n
Roei D. Mazor, MD<\/td>Biopsy Specimens of Erdheim-Chester Disease Patients<\/td>Not available<\/td>\n<\/tr>\n
Filip Janku, MD, PhD<\/td>Clinical Molecular Profiling to Detect Targetable Alterations in Archival Tumor Tissue and Cell-free DNA from Patients with Erdheim-Chester Disease<\/a><\/td>Clinical Molecular Profiling to Detect Targetable Alterations in Archival Tumor Tissue and Cell-free DNA from Patients with Erdheim-Chester Disease<\/a><\/td>\n<\/tr>\n
Tahla Munir, MD<\/td>A Single- centre Experience of Treating Adult Patients with Langerhans' cell
\nHistiocytosis and Erdheim Chester Disease; Sustained Response to Oral Methotrexate in Frontline and Relapsed Disease<\/td>		A Single- centre Experience of Treating Adult Patients with Langerhans' cellHistiocytosis and Erdheim Chester Disease; Sustained Response to Oral Methotrexate in Frontline and Relapsed Disease<\/a><\/td>\n<\/tr>\n
Achille Aouba, MD, PhD<\/td>Superior Efficacy and Equivalent Safety of Double-dose Anakinra in Erdheim-Chester Disease<\/td>Superior Efficacy and Equivalent Safety of Double-dose Anakinra in Erdheim-Chester Disease<\/a><\/td>\n<\/tr>\n
Tahla Munir, MD<\/td>Single Centre Experience of Treating Four Cases of Relapsed\/Refractory BRAF Mutated Erdheim Chester Disease (ECD) \/ Langerhan\u2019s Cell Histiocytosis(LCH) with Oral BRAF Inhibitor Vemurafenib<\/td>Single Centre Experience of Treating Four Cases of Relapsed\/Refractory BRAF Mutated Erdheim Chester Disease (ECD) \/ Langerhan\u2019s Cell Histiocytosis(LCH) with Oral BRAF Inhibitor Vemurafenib<\/a><\/td>\n<\/tr>\n
Fleur Cohen-Aubart, MD and Julien Haroche, MD, PhD<\/td>The LOVE trial: preliminary results<\/td>Not available<\/td>\n<\/tr>\n
Juvianee Estrada-Veras, MD<\/td>Dabrafenib and Trametinib as Potential Therapy in BRAF V600E Positive ErdheimChester Disease (ECD): Preliminary Results<\/td>Not available<\/td>\n<\/tr>\n
Eli L. Diamond, MD<\/td>Phase 2 Trial of Single-Agent Cobimetinib for Adults with Histiocytic Disorders: Preliminary Results<\/td>Not available<\/td>\n<\/tr>\n
Tahla Munir, MD<\/td>Dabrafenib in combination with Trametinib is effective in treatment of refractory BRAF mutated mixed histiocytic disease- A Case report<\/td>Dabrafenib in combination with Trametinib is effective in treatment of refractory BRAF mutated mixed histiocytic disease- A Case report<\/a><\/td>\n<\/tr>\n
Diana Melo, MD<\/td>Spectrum of Cardiovascular Involvement in Erdheim-Chester Disease Evaluated by Multimodality Imaging<\/td>Not available<\/td>\n<\/tr>\n
Mark Heaney, MD, Julien Haroche, MD, PhD, Eli L. Diamond, MD, Matthew Collin, MD, Lorenzo Dagna, MD, PhD<\/td>Panel Discussion: ECD Patient Registry: Community Tool for Research<\/td>Panel Discussion: ECD Patient Registry: Community Tool for Research<\/a><\/td>\n<\/tr>\n
Augusto Vaglio, MD, PhD, Juvianee Estrada-Veras, MD, Filip Janku, MD, PhD, Omar Abdel-Wahab, MD, PhD, Javier Martin, MD, PhD<\/td>Panel Discussion: Proposed ECD GWAS Study<\/a><\/td>Panel Discussion: Proposed ECD GWAS Study<\/a><\/td>\n<\/tr>\n
Corrado Campochiaro, MD<\/td>Management of ECD Symptoms and Side Effects of Treatments<\/a><\/td>Management of ECD Symptoms and Side Effects of Treatments<\/a><\/td>\n<\/tr>\n
Giulio Cavalli, MD<\/td>Adult Onset (Infratentorial) Leukoencephalopathy as Presenting Manifestation of Erdheim-Chester Disease<\/a><\/td>Adult Onset (Infratentorial) Leukoencephalopathy as Presenting Manifestation of Erdheim-Chester Disease<\/a><\/td>\n<\/tr>\n
Carine Courtillot, MD<\/td>Endocrine manifestations in Erdheim-Chester disease<\/a><\/td>Endocrine manifestations in Erdheim-Chester disease<\/a><\/td>\n<\/tr>\n
Benjamin Durham, MD<\/td>Insights into the Cell-of-Origin of the Histiocytoses Using Patient-Derived Xenograft Murine Models<\/a><\/td>Insights into the Cell-of-Origin of the Histiocytoses Using Patient-Derived Xenograft Murine Models<\/a><\/td>\n<\/tr>\n
Marina Ferrarini, MD<\/td>Tailoring Treatment for Erdheim-Chester Disease: Focus on ECD<\/a><\/td>Tailoring Treatment for Erdheim-Chester Disease: Focus on ECD<\/a><\/td>\n<\/tr>\n
Ronald Go, MD<\/td>Efficacy of Cladribine (2-CdA) in the Treatment of Erdheim-Chester Disease (ECD)<\/a><\/td>Efficacy of Cladribine (2-CdA) in the Treatment of Erdheim-Chester Disease (ECD)<\/a><\/td>\n<\/tr>\n
Filip Janku, MD, PhD<\/td>Encouraging activity of MEK inhibitor trametinib in patients with Erdheim-Chester disease irrespective of BRAF mutation statusClinical Molecular Profiling to Detect Targetable Alterations in Archival Tumor Tissue and Cell-free DNA from Patients with Erdheim-Chester Disease<\/a><\/td>Encouraging activity of MEK inhibitor trametinib in patients with Erdheim-Chester disease irrespective of BRAF mutation statusClinical Molecular Profiling to Detect Targetable Alterations in Archival Tumor Tissue and Cell-free DNA from Patients with Erdheim-Chester Disease<\/a><\/td>\n<\/tr>\n
Javier Martin, MD, PhD<\/td>Future Genetic Studies in Erdheim-Chester disease \u2013 GWAS Study<\/a><\/td>Future Genetic Studies in Erdheim-Chester disease \u2013 GWAS Study<\/a><\/td>\n<\/tr>\n
Kenneth McClain, MD, PhD<\/td>Elevated CSF Osteopontin and Circulating Cells with BRAF Mutations in Patients with Langerhans Cell Histiocytosis-Associated Neurodegeneration -A Model for ECD?<\/a><\/td>Elevated CSF Osteopontin and Circulating Cells with BRAF Mutations in Patients with Langerhans Cell Histiocytosis-Associated Neurodegeneration -A Model for ECD?<\/a><\/td>\n<\/tr>\n
Augusto Vaglio, MD, PhD<\/td>MRI evidence of cardiac involvement in Erdheim-Chester disease<\/a><\/td>MRI evidence of cardiac involvement in Erdheim-Chester disease<\/a><\/td>\n<\/tr>\n
Julien Haroche, MD, PhD & Kathleen Brewer<\/td>Closing<\/td>Not available<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Groepsfoto Medisch Symposium Parijs 2016 Samenvatting symposiumDe Erdheim-Chester Disease Global Alliance is verheugd u de volgende samenvatting te kunnen aanbieden van de presentaties die zijn gegeven tijdens het 4e jaarlijkse […]<\/p>\n","protected":false},"author":20,"featured_media":135339,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","cybocfi_hide_featured_image":"","wds_primary_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[4825],"tags":[],"class_list":["post-102084","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medisch-symposium"],"_links":{"self":[{"href":"https:\/\/www.erdheim-chester.org\/nl\/wp-json\/wp\/v2\/posts\/102084","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.erdheim-chester.org\/nl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.erdheim-chester.org\/nl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/nl\/wp-json\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/nl\/wp-json\/wp\/v2\/comments?post=102084"}],"version-history":[{"count":0,"href":"https:\/\/www.erdheim-chester.org\/nl\/wp-json\/wp\/v2\/posts\/102084\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/nl\/wp-json\/wp\/v2\/media\/135339"}],"wp:attachment":[{"href":"https:\/\/www.erdheim-chester.org\/nl\/wp-json\/wp\/v2\/media?parent=102084"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/nl\/wp-json\/wp\/v2\/categories?post=102084"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/nl\/wp-json\/wp\/v2\/tags?post=102084"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}