{"id":53465,"date":"2025-05-07T09:18:02","date_gmt":"2025-05-07T13:18:02","guid":{"rendered":"https:\/\/www.erdheim-chester.org\/?p=53465"},"modified":"2025-05-17T15:00:55","modified_gmt":"2025-05-17T19:00:55","slug":"keynote-spotlight-dr-jerome-razanamahery","status":"publish","type":"post","link":"https:\/\/www.erdheim-chester.org\/hi\/keynote-spotlight-dr-jerome-razanamahery\/","title":{"rendered":"Keynote Spotlight: Dr. Jerome Razanamahery"},"content":{"rendered":"

Title: \u201cLayers of Complexity: ECD Diagnosis and Management in the Presence of Confounding Comorbidities\u201d<\/strong>
\nTime: 1:30 PM \u2013 1:55 PM<\/strong>
\nLocation: Bellvitge University Hospital Auditorium<\/strong><\/p>\n

As Erdheim-Chester Disease (ECD) becomes more recognized and understood within the medical community, a new challenge is emerging: what happens when a patient\u2019s symptoms don\u2019t follow a predictable pattern,\u00a0or worse, when ECD isn\u2019t the only condition at play?<\/p>\n

In this critical session, Dr. Jerome Razanamahery<\/strong> of Dijon University Hospital brings his expertise to the forefront, addressing the diagnostic and therapeutic complexities of ECD when it presents alongside other diseases<\/strong>. His talk, \u201cLayers of Complexity,\u201d is one of the most important of the day for clinicians who manage rare disease cases with overlapping or unclear clinical features.<\/p>\n

The Diagnostic Challenge<\/h3>\n

ECD is a disease of many faces. It can affect bones, the central nervous system, kidneys, cardiovascular structures, and other organs. Symptoms vary widely and often mimic more common illnesses. Add to this a second (or third) comorbid condition\u2014such as autoimmune disease, malignancy, or vascular inflammation\u2014and the picture becomes even more clouded.<\/p>\n

In this session, Dr. Razanamahery will explore:<\/p>\n

    \n
  • How misdiagnosis or delayed diagnosis<\/strong> often occurs when ECD is masked by more dominant or familiar comorbid presentations<\/li>\n
  • What clinical tools, imaging strategies, and molecular insights can help disentangle overlapping pathologies<\/strong><\/li>\n
  • Case examples where ECD was misinterpreted as sarcoidosis, vasculitis, or malignancy,\u00a0and what lessons were learned<\/li>\n
  • The importance of a multidisciplinary approach<\/strong>, particularly when treatment for one condition may inadvertently worsen another<\/li>\n<\/ul>\n

    Expertise in Complex Cases<\/h3>\n

    Dr. Razanamahery leads a recognized Center of Competence for Histiocytic Disorders<\/strong> in Dijon, France, where his team specializes in tackling diagnostically ambiguous or high-complexity cases. He is known for bridging internal medicine with clinical immunology, drawing on a broad toolkit to manage patients with rare and overlapping diseases.<\/p>\n

    This talk is especially relevant for physicians who work in:<\/p>\n

      \n
    • General Internal Medicine<\/strong><\/li>\n
    • Hematology\/Oncology<\/strong><\/li>\n
    • Rheumatology<\/strong><\/li>\n
    • Immunology<\/strong><\/li>\n
    • Neurology<\/strong><\/li>\n
    • Nephrology<\/strong><\/li>\n<\/ul>\n

      These specialties frequently encounter patients with multisystem involvement and may be among the first to recognize ECD\u2014especially when the disease does not appear in isolation.<\/p>\n

      The Broader Implications for ECD Care<\/h3>\n

      One of the themes of this year\u2019s Medical Symposium is refining real-world diagnosis and care pathways<\/strong> for Erdheim-Chester Disease. As molecular tools and clinical awareness improve, new layers of complexity are surfacing, particularly in cases where ECD is not the only condition altering the patient\u2019s health.<\/p>\n

      Dr. Razanamahery\u2019s presentation underscores the need for nuanced care, cautious diagnostics, and collaboration across specialties. It also highlights the reality that ECD rarely exists in a vacuum<\/strong>\u2014and that advancing care will require not just more science, but deeper clinical insight into how ECD interacts with the full human experience of health and illness.<\/p>\n

      Don\u2019t Miss This Talk<\/h3>\n

      If you\u2019ve ever encountered a patient whose symptoms seemed contradictory, whose imaging didn\u2019t fit the mold, or whose response to treatment raised new questions,\u00a0this is the session for you. Dr. Razanamahery\u2019s work is a reminder that treating ECD isn\u2019t just about following a protocol; it\u2019s about understanding the whole person and the full context of their care.<\/p>\n

      This keynote exemplifies the purpose of the ECDGA Medical Symposium: to bring together knowledge, challenge assumptions, and improve outcomes through collaboration and clarity.<\/p>","protected":false},"excerpt":{"rendered":"

      Title: \u201cLayers of Complexity: ECD Diagnosis and Management in the Presence of Confounding Comorbidities\u201d Time: 1:30 PM \u2013 1:55 PM Location: Bellvitge University Hospital Auditorium As Erdheim-Chester Disease (ECD) becomes […]<\/p>\n","protected":false},"author":14,"featured_media":53586,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","cybocfi_hide_featured_image":"","wds_primary_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[51],"tags":[594,375,378,387,380,383,374,384,386,376,385],"class_list":["post-53465","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-barcelona","tag-ecdawareness","tag-ecdcommunity","tag-ecdga","tag-ecdsupport","tag-ecdvolunteer","tag-erdheimchesterdisease","tag-hopeforecd","tag-makerarevisible","tag-raredisease","tag-supportraredisease"],"_links":{"self":[{"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/posts\/53465","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/comments?post=53465"}],"version-history":[{"count":0,"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/posts\/53465\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/media\/53586"}],"wp:attachment":[{"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/media?parent=53465"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/categories?post=53465"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/tags?post=53465"}],"curies":[{"name":"\u0921\u092c\u094d\u0932\u094d\u092f\u0942\u092a\u0940","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}