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\u0915\u0947\u0902\u0926\u094d\u0930 \u0915\u0947 \u092a\u093e\u0938 \u0928 \u0939\u094b\u0902, \u092b\u093f\u0930 \u092d\u0940 \u0906\u092a\u0915\u094b \u092f\u093e \u0909\u092a\u091a\u093e\u0930 \u0915\u0930\u0928\u0947 \u0935\u093e\u0932\u0947 \u0921\u0949\u0915\u094d\u091f\u0930 \u0915\u094b \u0909\u092a\u091a\u093e\u0930 \u0938\u0947 \u092a\u0939\u0932\u0947 \u092a\u0930\u0940\u0915\u094d\u0937\u0923\/\u0905\u0927\u094d\u092f\u092f\u0928 \u092e\u0947\u0902 \u0936\u093e\u092e\u093f\u0932 \u0936\u094b\u0927\u0915\u0930\u094d\u0924\u093e\u0913\u0902 \u092e\u0947\u0902 \u0938\u0947 \u0915\u093f\u0938\u0940 \u090f\u0915 \u0938\u0947 \u092c\u093e\u0924 \u0915\u0930\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u092a\u094d\u0930\u094b\u0924\u094d\u0938\u093e\u0939\u093f\u0924 \u0915\u093f\u092f\u093e \u091c\u093e\u0924\u093e \u0939\u0948\u0964 \u0907\u0938\u0938\u0947 \u0906\u092a\u0915\u094b ECD \u0909\u092a\u091a\u093e\u0930\u094b\u0902 \u0915\u0940 \u0924\u0947\u091c\u093c\u0940 \u0938\u0947 \u092c\u0926\u0932\u0924\u0940 \u0926\u0941\u0928\u093f\u092f\u093e \u092e\u0947\u0902 \u0915\u0941\u091b \u0905\u0917\u094d\u0930\u0923\u0940 \u0936\u094b\u0927\u094b\u0902 \u0938\u0947 \u0932\u093e\u092d \u0909\u0920\u093e\u0928\u0947 \u0915\u093e \u092e\u094c\u0915\u093e \u092e\u093f\u0932\u0947\u0917\u093e\u0964 <\/p>\n<h3>\u0905\u0927\u094d\u092f\u092f\u0928 \u0915\u0930\u0924\u0947 \u0939\u0948\u0902<\/h3>\n<p>ECD \u0905\u0928\u0941\u0938\u0902\u0927\u093e\u0928 \u092e\u0947\u0902 \u0905\u0935\u0932\u094b\u0915\u0928 \u0938\u0902\u092c\u0902\u0927\u0940 \u0905\u0927\u094d\u092f\u092f\u0928 \u0914\u0930 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u200b\u200b\u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0936\u093e\u092e\u093f\u0932 \u0939\u0948\u0902\u0964 \u0905\u0935\u0932\u094b\u0915\u0928 \u0938\u0902\u092c\u0902\u0927\u0940 \u0905\u0927\u094d\u092f\u092f\u0928 \u0909\u092a\u091a\u093e\u0930\u094b\u0902 \u0915\u093e \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0928\u0939\u0940\u0902 \u0915\u0930\u0924\u0947 \u0939\u0948\u0902, \u092c\u0932\u094d\u0915\u093f \u090f\u0915 \u092a\u0930\u093f\u0915\u0932\u094d\u092a\u0928\u093e \u0935\u093f\u0915\u0938\u093f\u0924 \u0915\u0930\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0915\u093f\u0938\u0940 \u0938\u094d\u0925\u093f\u0924\u093f \u0915\u093e \u0928\u093f\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u0930\u0924\u0947 \u0939\u0948\u0902, \u091c\u093f\u0938\u0947 \u092b\u093f\u0930 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u200b\u200b\u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u0947 \u092e\u093e\u0927\u094d\u092f\u092e \u0938\u0947 \u092a\u0930\u0916\u093e \u091c\u093e \u0938\u0915\u0924\u093e \u0939\u0948\u0964 \u0905\u0927\u094d\u092f\u092f\u0928 \u0914\u0930 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u200b\u200b\u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0926\u094b\u0928\u094b\u0902 \u092e\u0947\u0902 \u0939\u0940 ECD \u0915\u0947 \u092c\u093e\u0930\u0947 \u092e\u0947\u0902 \u0905\u0927\u093f\u0915 \u091c\u093e\u0928\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0906\u0935\u0936\u094d\u092f\u0915 \u0936\u094b\u0927 \u0915\u0930\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0915\u094b \u0936\u093e\u092e\u093f\u0932 \u0939\u094b\u0928\u0947 \u0915\u0940 \u0906\u0935\u0936\u094d\u092f\u0915\u0924\u093e \u0939\u094b\u0924\u0940 \u0939\u0948\u0964  <\/p>\n<h3>\u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u092a\u0930\u0940\u0915\u094d\u0937\u0923<\/h3>\n<p>\u0935\u0930\u094d\u0924\u092e\u093e\u0928 \u092e\u0947\u0902 ECD \u0909\u092a\u091a\u093e\u0930 \u0915\u0947 \u0932\u093f\u090f \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u200b\u200b\u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0916\u0941\u0932\u0947 \u0939\u0948\u0902\u0964 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u092e\u0947\u0902 \u0936\u093e\u092e\u093f\u0932 \u0939\u094b\u0928\u0947 \u0938\u0947 \u092e\u0930\u0940\u091c \u0915\u094b 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\u0915\u0947 \u092e\u093e\u0927\u094d\u092f\u092e \u0938\u0947 \u092c\u0921\u093c\u0947 \u092a\u0948\u092e\u093e\u0928\u0947 \u092a\u0930 \u0938\u0902\u092c\u094b\u0927\u093f\u0924 \u0915\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948, \u091c\u093f\u0938\u0915\u0947 \u0924\u0939\u0924 \u091a\u093f\u0915\u093f\u0924\u094d\u0938\u0915\u0940\u092f \u0930\u0942\u092a \u0938\u0947 \u0909\u092a\u092f\u0941\u0915\u094d\u0924 \u0915\u0948\u0902\u0938\u0930 \u0909\u092a\u091a\u093e\u0930\u094b\u0902 \u0915\u094b \u092c\u0940\u092e\u093e \u0926\u094d\u0935\u093e\u0930\u093e \u0915\u0935\u0930 \u0915\u093f\u092f\u093e \u091c\u093e\u0928\u093e \u0906\u0935\u0936\u094d\u092f\u0915 \u0939\u0948\u0964 \u0907\u0938 \u0915\u093e\u0928\u0942\u0928 \u092e\u0947\u0902 \u0911\u092b-\u0932\u0947\u092c\u0932 \u0909\u092a\u092f\u094b\u0917 \u0936\u093e\u092e\u093f\u0932 \u0939\u0948\u0902, \u092f\u0926\u093f \u0909\u092a\u091a\u093e\u0930 \u0915\u093e \u0938\u093e\u0935\u0927\u093e\u0928\u0940\u092a\u0942\u0930\u094d\u0935\u0915 \u0936\u094b\u0927 \u0905\u0927\u094d\u092f\u092f\u0928\u094b\u0902 \u092e\u0947\u0902 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948 \u0914\u0930 \u092a\u094d\u0930\u0924\u093f\u0937\u094d\u0920\u093f\u0924 \u0926\u0935\u093e \u0938\u0902\u0926\u0930\u094d\u092d \u092a\u0941\u0938\u094d\u0924\u0915\u094b\u0902 \u092f\u093e \u091a\u093f\u0915\u093f\u0924\u094d\u0938\u093e \u092a\u0924\u094d\u0930\u093f\u0915\u093e\u0913\u0902 \u092e\u0947\u0902 \u0907\u0938\u0915\u093e \u0935\u0930\u094d\u0923\u0928 \u0915\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948\u0964 2008 \u092e\u0947\u0902, \u092e\u0947\u0921\u093f\u0915\u0947\u092f\u0930 \u0928\u093f\u092f\u092e\u094b\u0902 \u0915\u094b \u0915\u0948\u0902\u0938\u0930 \u0909\u092a\u091a\u093e\u0930 \u0926\u0935\u093e\u0913\u0902 \u0915\u0947 \u0905\u0927\u093f\u0915 \u0911\u092b-\u0932\u0947\u092c\u0932 \u0909\u092a\u092f\u094b\u0917\u094b\u0902 \u0915\u094b \u0915\u0935\u0930 \u0915\u0930\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u092c\u0926\u0932 \u0926\u093f\u092f\u093e \u0917\u092f\u093e \u0925\u093e\u0964  <\/p>\n<p>\u092b\u093f\u0930 \u092d\u0940, \u0938\u094d\u0935\u093e\u0938\u094d\u0925\u094d\u092f \u092c\u0940\u092e\u093e \u0915\u0935\u0930\u0947\u091c \u0915\u093e\u0928\u0942\u0928 \u0914\u0930 \u0935\u093f\u0928\u093f\u092f\u092e \u091c\u091f\u093f\u0932 \u0939\u0948\u0902\u0964 \u092f\u0926\u093f \u0906\u092a\u0915\u093e \u0921\u0949\u0915\u094d\u091f\u0930 \u0911\u092b-\u0932\u0947\u092c\u0932 \u0921\u094d\u0930\u0917 \u0909\u092a\u092f\u094b\u0917 \u0915\u0947 \u092c\u093e\u0930\u0947 \u092e\u0947\u0902 \u0938\u094b\u091a \u0930\u0939\u093e \u0939\u0948, \u0924\u094b \u0906\u092a\u0915\u094b \u0914\u0930 \u0906\u092a\u0915\u0947 \u0921\u0949\u0915\u094d\u091f\u0930 \u0915\u094b \u0906\u092a\u0915\u0940 \u0938\u094d\u0935\u093e\u0938\u094d\u0925\u094d\u092f \u092f\u094b\u091c\u0928\u093e \u0915\u0947 \u0915\u0935\u0930\u0947\u091c \u0915\u0940 \u0938\u093e\u0935\u0927\u093e\u0928\u0940\u092a\u0942\u0930\u094d\u0935\u0915 \u091c\u093e\u0902\u091a \u0915\u0930\u0928\u0940 \u091a\u093e\u0939\u093f\u090f\u0964 \u092f\u0926\u093f \u0906\u092a\u0915\u094b \u0915\u0935\u0930\u0947\u091c \u0938\u0947 \u0935\u0902\u091a\u093f\u0924 \u0915\u093f\u092f\u093e \u091c\u093e\u0924\u093e \u0939\u0948, \u0924\u094b \u092f\u0939 \u092e\u0926\u0926 \u0915\u0930 \u0938\u0915\u0924\u093e \u0939\u0948 \u092f\u0926\u093f \u0921\u0949\u0915\u094d\u091f\u0930 \u092c\u0940\u092e\u093e\u0915\u0930\u094d\u0924\u093e \u0915\u094b \u0938\u0939\u0915\u0930\u094d\u092e\u0940-\u0938\u092e\u0940\u0915\u094d\u0937\u093f\u0924 \u091c\u0930\u094d\u0928\u0932 \u0932\u0947\u0916\u094b\u0902 \u092f\u093e \u0905\u0928\u094d\u092f \u0938\u092e\u094d\u092e\u093e\u0928\u093f\u0924 \u0938\u094d\u0930\u094b\u0924\u094b\u0902 \u0915\u0940 \u092a\u094d\u0930\u0924\u093f\u092f\u093e\u0902 \u092d\u0947\u091c\u0924\u093e \u0939\u0948 \u091c\u094b \u0911\u092b-\u0932\u0947\u092c\u0932 \u0909\u092a\u092f\u094b\u0917 \u0915\u093e \u0938\u092e\u0930\u094d\u0925\u0928 \u0915\u0930\u0924\u0947 \u0939\u0948\u0902\u0964 ECD \u0917\u094d\u0932\u094b\u092c\u0932 \u0905\u0932\u093e\u092f\u0902\u0938 \u0907\u0938 \u092e\u093e\u092e\u0932\u0947 \u092e\u0947\u0902 \u092e\u0947\u0921\u093f\u0915\u0932 \u091f\u0940\u092e\u094b\u0902 \u0915\u0940 \u092e\u0926\u0926 \u0915\u0930\u0928\u0947 \u092e\u0947\u0902 \u092a\u094d\u0930\u0938\u0928\u094d\u0928 \u0939\u0948\u0964 (\u0915\u0943\u092a\u092f\u093e \u0939\u092e\u093e\u0930\u093e \u092a\u0947\u091c \u0926\u0947\u0916\u0947\u0902 <a href=\"https:\/\/www.erdheim-chester.org\/hi\/%e0%a4%ad%e0%a5%81%e0%a4%97%e0%a4%a4%e0%a4%be%e0%a4%a8%e0%a4%95%e0%a4%b0%e0%a5%8d%e0%a4%a4%e0%a4%be-%e0%a4%85%e0%a4%aa%e0%a5%80%e0%a4%b2-%e0%a4%a6%e0%a4%be%e0%a4%96%e0%a4%bf%e0%a4%b2-%e0%a4%95\/\">\u092d\u0941\u0917\u0924\u093e\u0928\u0915\u0930\u094d\u0924\u093e \u0905\u092a\u0940\u0932 \u0926\u093e\u0916\u093f\u0932 \u0915\u0930\u0928\u093e<\/a> \u0964)    <\/p>\n<p>[\/et_pb_text][et_pb_text module_id=&#8221;trials&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h2>\u0935\u0930\u094d\u0924\u092e\u093e\u0928 \u0913\u092a\u0928 ECD \u0905\u0927\u094d\u092f\u092f\u0928 \u0914\u0930 \u092a\u0930\u0940\u0915\u094d\u0937\u0923<\/h2>\n<div class=\"tp-sticky-wrap\">\n\n<table id=\"tablepress-1\" class=\"tablepress tablepress-id-1 tablepress-responsive tablepress-responsive-stack-headers tablepress-responsive-stack-phone\">\n<thead>\n<tr class=\"row-1\">\n\t<th class=\"column-1\"><strong>#<\/strong><\/th><th class=\"column-2\"><strong>NCT#<\/strong><\/th><th class=\"column-3\"><strong>Name of Study<\/strong><\/th><th class=\"column-4\"><strong>Purpose<\/strong><\/th><th class=\"column-5\"><strong>Type of Study<\/strong><\/th><th class=\"column-6\"><strong>Selection<\/strong><\/th><th class=\"column-7\"><strong>Age Requirement<\/strong><\/th><th class=\"column-8\"><strong>Care Center \/ Contact<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-striping row-hover\">\n<tr class=\"row-2\">\n\t<td class=\"column-1\">1<\/td><td class=\"column-2\"><a href=\"https:\/\/classic.clinicaltrials.gov\/ct2\/show\/NCT05915208?id=NCT05915208&#038;draw=2&#038;rank=1\"target=\"_blank\">NCT05915208<\/a><\/td><td class=\"column-3\">Histiocytic Disorder Follow-up Study<\/td><td class=\"column-4\">To understand the health problems experienced by individuals with ECD and other histiocytic disorders.<\/td><td class=\"column-5\">Surveys only<br \/>\nObservational<br \/>\nRetrospective<\/td><td class=\"column-6\">English survey completion (online, on phone, or on paper) from the comfort of your home.<\/td><td class=\"column-7\">18 \u2013 89 years old<\/td><td class=\"column-8\">University of Alabama at Birmingham<br \/>\nBirmingham, AL  USA<br \/>\nGaurav Goyal, MD<br \/>\nhistio@uabmc.edu<br \/>\n+1-866-438-1640<\/td>\n<\/tr>\n<tr class=\"row-3\">\n\t<td class=\"column-1\">2<\/td><td class=\"column-2\"><a href=\"https:\/\/classic.clinicaltrials.gov\/ct2\/show\/NCT03329274?id=NCT03329274&#038;draw=2&#038;rank=1\"target=\"_blank\">NCT03329274<\/a><\/td><td class=\"column-3\">Registry for Patients with Erdheim-Chester Disease and Other Histiocytoses<\/td><td class=\"column-4\">Determine what kinds of health problems are caused by histiocytosis, what happens as a result of different treatments, and how ECD affects people's lives, their feelings and their attitudes.<\/td><td class=\"column-5\">Surveys &amp; medical records<br \/>\nObservational<br \/>\nProspective<\/td><td class=\"column-6\">Erdheim-Chester Disease, Langerhans cell histiocytosis, Rosai Dorfman disease, or another histiocytic neoplasm<\/td><td class=\"column-7\">18 years and older<\/td><td class=\"column-8\">MSKCC<br \/>\nNew York City, NY  USA<br \/>\nEli Diamond, MD<br \/>\ndiamone1@mskcc.org<br \/>\n+1- 212-610-0243<\/td>\n<\/tr>\n<tr class=\"row-4\">\n\t<td class=\"column-1\">3<\/td><td class=\"column-2\"><a href=\"https:\/\/classic.clinicaltrials.gov\/ct2\/show\/NCT03990428?id=NCT03990428&#038;draw=2&#038;rank=1\"target=\"_blank\">NCT03990428<\/a><\/td><td class=\"column-3\">Supportive Care Needs of Caregivers of People with Erdheim-Chester Disease and Other Histiocytic Diseases<\/td><td class=\"column-4\">Determine the supportive care needs of informal caregivers of people with Erdheim-Chester disease and other histiocytic diseases<\/td><td class=\"column-5\">Online surveys<br \/>\nObservational<br \/>\nProspective<\/td><td class=\"column-6\">Self id\u2019d unpaid support person for ECD, LCH, RDD, or JXG patient<\/td><td class=\"column-7\">18 years and older<\/td><td class=\"column-8\">MSKCC<br \/>\nNew York City, NY  USA<br \/>\nEli Diamond, MD<br \/>\ndiamone1@mskcc.org<br \/>\n+1- 212-610-0243<\/td>\n<\/tr>\n<tr class=\"row-5\">\n\t<td class=\"column-1\">4<\/td><td class=\"column-2\"><a href=\"https:\/\/classic.clinicaltrials.gov\/ct2\/show\/NCT03017820?id=NCT03017820&#038;draw=2&#038;rank=1\"target=\"_blank\">NCT03017820<\/a><\/td><td class=\"column-3\">VSV-hIFNbeta-NIS in Treating Patients With Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma<\/td><td class=\"column-4\">Studies the best dose and side effects of recombinant vesicular stomatitis virus carrying the human NIS and IFN beta genes as a way to to kill cancer cells without damaging normal cells.  For patients whose prior treatment did not help<\/td><td class=\"column-5\">Clinical Trial<br \/>\nInterventional Treatment<\/td><td class=\"column-6\">Relapsed\/ refractory to prior ECD treatments<\/td><td class=\"column-7\">18 years and older<\/td><td class=\"column-8\">Mayo Clinic in Rochester<br \/>\nRochester, MN  USA<br \/>\nNora Bennani, MD<br \/>\nRonald Go, MD<br \/>\ngo.ronald@mayo.edu<\/td>\n<\/tr>\n<tr class=\"row-6\">\n\t<td class=\"column-1\">5<\/td><td class=\"column-2\"><a href=\"https:\/\/classic.clinicaltrials.gov\/ct2\/show\/NCT04640779?id=NCT04640779&#038;draw=2&#038;rank=1\"target=\"_blank\">NCT04640779<\/a><\/td><td class=\"column-3\">Low-Dose Selinexor and Choline Salicylate for Non-Hodgkin or Hodgkin Lymphoma, Histiocytic\/Dendritic Cell Neoplasm, or Relapsed or Refractory Multiple Myeloma<\/td><td class=\"column-4\">Evaluates the side effects and best dose of choline salicylate given together for patients whose prior treatment did not help.<\/td><td class=\"column-5\">Clinical Trial<br \/>\nInterventional Treatment<\/td><td class=\"column-6\">Relapsed\/ refractory to prior ECD treatments<\/td><td class=\"column-7\">18 years and older<\/td><td class=\"column-8\">Mayo Clinic in Rochester<br \/>\nRochester, MN  USA<br \/>\nJonas Paludo, M.D.   <br \/>\nRonald Go, MD<br \/>\ngo.ronald@mayo.edu<\/td>\n<\/tr>\n<tr class=\"row-7\">\n\t<td class=\"column-1\">6<\/td><td class=\"column-2\"><a href=\"https:\/\/classic.clinicaltrials.gov\/ct2\/show\/NCT06153173?id=NCT06153173&#038;draw=2&#038;rank=1\"target=\"_blank\">NCT06153173<\/a><\/td><td class=\"column-3\">Mirdametinib in Histiocytic Disorders<\/td><td class=\"column-4\">Determine if treatment with mirdametinib in patients with histiocytic disorders will be better than current treatments and with fewer side effects.<\/td><td class=\"column-5\">Clinical Trial<br \/>\nInterventional Treatment<\/td><td class=\"column-6\">Diagnosis of histiocytic neoplasm confirmed by a Cincinnati Children's Hospital pathologist. Exception for those with isolated pituitary\/CNS disease where biopsy is not feasible.<\/td><td class=\"column-7\">2 years and older<\/td><td class=\"column-8\">Children's Hospital Medical Center<br \/>\nCincinnati, Ohio  USA<br \/>\nMonica Trapp<br \/>\nmonica.trapp@cchmc.org<br \/>\nAshish Kumar, MD, PhD<br \/>\n+1-513-803-8574<\/td>\n<\/tr>\n<tr class=\"row-8\">\n\t<td class=\"column-1\">7<\/td><td class=\"column-2\">n\/a<\/td><td class=\"column-3\">LCH and Vitamin D<\/td><td class=\"column-4\">To investigate changes in the skeletal related quality of life (QoL) among adult LCH patients following a 3-month cholecalciferol supplementation to achieve or maintain 25(OH)D levels \u2265 30 ng\/ml (75 nmol\/L).<\/td><td class=\"column-5\">Clinical Trial<br \/>\nInterventional Adjunct Therapy<\/td><td class=\"column-6\">Histiocytosis diagnosis<\/td><td class=\"column-7\">All ages?<\/td><td class=\"column-8\">251 Hellenic Air Force &amp; VA General Hospital<br \/>\nGreece<br \/>\nMakras Polyzois, MD  <br \/>\ninfo@adultlch.gr<br \/>\n30-2107463606<\/td>\n<\/tr>\n<tr class=\"row-9\">\n\t<td class=\"column-1\">8<\/td><td class=\"column-2\"><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06411821?intr=ulixertinib&#038;rank=1\"target=\"_blank\">NCT06411821<\/a><\/td><td class=\"column-3\">Phase 2 Trial of Ulixertinib for Patients with Histiocytic Neoplasms<\/td><td class=\"column-4\">Clinical trial of oral ERK inhibitor<\/td><td class=\"column-5\">Clinical Trial<br \/>\nInterventional Treatment<\/td><td class=\"column-6\">Any histiocytic neoplasm<\/td><td class=\"column-7\">18 years and older<\/td><td class=\"column-8\">MSKCC<br \/>\nNYC, NY  USA<br \/>\nEli  Diamond, MD <br \/>\ndiamone1@mskcc.org<\/td>\n<\/tr>\n<tr class=\"row-10\">\n\t<td class=\"column-1\">9<\/td><td class=\"column-2\"><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT04079179?id=NCT04079179&#038;rank=1\"target=\"_blank\">NCT04079179<\/a><\/td><td class=\"column-3\">Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders (NACHO-COBI)<\/td><td class=\"column-4\">Study of cobimetinib in children and adults with LCH and other histiocytic diorders.<\/td><td class=\"column-5\">Clinical Trial<br \/>\nInterventional Treatment<\/td><td class=\"column-6\">Relapsed\/ refractory to prior ECD treatments<\/td><td class=\"column-7\">6 months and older<\/td><td class=\"column-8\">NACHO (Baltimore, Dallas, DC, Houston, Madison, Memphis, Orange, ??)<br \/>\nTexas Children\u2019s Hospital<br \/>\nHouston, TX  USA<br \/>\nCarl Allen, MD  <br \/>\nceallen@texaschildrens.org<br \/>\n+1-832-822-4242<\/td>\n<\/tr>\n<tr class=\"row-11\">\n\t<td class=\"column-1\">10<\/td><td class=\"column-2\"><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05768178?term=NCT05768178&#038;rank=1\"target=\"_blank\">NCT05768178<\/a><\/td><td class=\"column-3\">Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.<\/td><td class=\"column-4\">Evaluate the efficacy of vemurafenib and cobimetinib in adult patients with rare cancers with BRAF V600 mutations.<\/td><td class=\"column-5\">Clinical Trial<br \/>\nInterventional Treatment<\/td><td class=\"column-6\">BRAF V600E<\/td><td class=\"column-7\">16 years and older<\/td><td class=\"column-8\">Multiple UK Hospitals<br \/>\nIncluding Leeds General Infirmary<br \/>\nLeeds, UK<br \/>\nMartin Elliott, MBBS<br \/>\nMartin.elliott1@nhs.net<br \/>\n0113 392 8779<\/td>\n<\/tr>\n<tr class=\"row-12\">\n\t<td class=\"column-1\">11<\/td><td class=\"column-2\"><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT02925234?term=NCT02925234&#038;rank=1\"target=\"_blank\">NCT02925234<\/a><\/td><td class=\"column-3\">The Drug Rediscovery Protocol (DRUP Trial) (DRUP)<\/td><td class=\"column-4\">A drug-access program, in which patients are treated with registered targeted therapy matched to their molecular tumor profile.<\/td><td class=\"column-5\">Clinical Trial<br \/>\n<\/td><td class=\"column-6\">Histologically-proven disease<\/td><td class=\"column-7\">18 years and older<\/td><td class=\"column-8\">Erasmus MC<br \/>\nRotterdam, Netherlands<br \/>\nM.J.A. de Jonge, MD, PhD<br \/>\nE.E. Voest, prof.<br \/>\n0031205129111<br \/>\nDRUP@nki.nl<br \/>\n <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[et_pb_dmb_breadcrumbs _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; body_text_color=&#8221;#FFFFFF&#8221; body_font_size=&#8221;12px&#8221; link_text_color=&#8221;#35A4BB&#8221; custom_margin=&#8221;||5px||false|false&#8221; custom_padding=&#8221;||0px||false|false&#8221; body_font_size_tablet=&#8221;12px&#8221; body_font_size_phone=&#8221;10px&#8221; body_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_dmb_breadcrumbs]\u0935\u0930\u094d\u0924\u092e\u093e\u0928 \u092e\u0947\u0902 ECD \u092a\u0930\u0940\u0915\u094d\u0937\u0923\/\u0905\u0927\u094d\u092f\u092f\u0928 \u091a\u0932 \u0930\u0939\u0947 \u0939\u0948\u0902 \u091c\u093f\u0928\u092e\u0947\u0902 ECD \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0915\u094b \u0938\u094d\u0935\u0940\u0915\u093e\u0930 \u0915\u093f\u092f\u093e \u091c\u093e \u0930\u0939\u093e \u0939\u0948\u0964 \u092d\u0932\u0947 \u0939\u0940 \u0906\u092a [&hellip;]<\/p>\n","protected":false},"author":14,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_wds_title":"","_wds_metadesc":"","_wds_focus-keywords":"","_wds_meta-robots-adv":"","_wds_meta-robots-noindex":false,"_wds_meta-robots-nofollow":false,"_wds_meta-robots-index":false,"_wds_meta-robots-follow":false,"_wds_autolinks-exclude":false,"_wds_canonical":"","_wds_redirect":"","_wds_opengraph":[],"_wds_twitter":[],"cybocfi_hide_featured_image":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-57515","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/pages\/57515","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/comments?post=57515"}],"version-history":[{"count":0,"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/pages\/57515\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.erdheim-chester.org\/hi\/wp-json\/wp\/v2\/media?parent=57515"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}