{"id":113541,"date":"2026-02-01T11:11:23","date_gmt":"2026-02-01T17:11:23","guid":{"rendered":"https:\/\/www.erdheim-chester.org\/?p=113541"},"modified":"2026-02-11T16:49:43","modified_gmt":"2026-02-11T22:49:43","slug":"%d7%94%d7%a1%d7%91%d7%a8-%d7%a2%d7%9c-%d7%9e%d7%97%d7%9c%d7%aa-%d7%90%d7%a8%d7%93%d7%94%d7%99%d7%99%d7%9d-%d7%a6%d7%a1%d7%98%d7%a8-%d7%aa%d7%a1%d7%9e%d7%99%d7%a0%d7%99%d7%9d-%d7%90%d7%91%d7%97","status":"publish","type":"post","link":"https:\/\/www.erdheim-chester.org\/he\/erdheim-chester-disease-explained-symptoms-diagnosis-research-advances\/","title":{"rendered":"\u05e1\u05de\u05d9\u05e0\u05e8 \u05de\u05e7\u05d5\u05d5\u05df \u05d1\u05e6\u05e8\u05e4\u05ea\u05d9\u05ea \u05e2\u05dd \u05d3\"\u05e8 \u05d2'\u05e8\u05d5\u05dd \u05e8\u05d6\u05e0\u05de\u05d4\u05e8\u05d9: \u05e4\u05d9\u05e2\u05e0\u05d5\u05d7 \u05d4-ECD \u2013 \u05d0\u05d1\u05d7\u05d5\u05df \u05d5\u05d8\u05d9\u05e4\u05d5\u05dc\u05d9\u05dd"},"content":{"rendered":"<p>\u05d1\u05e1\u05de\u05d9\u05e0\u05e8 \u05d4\u05de\u05e7\u05d5\u05d5\u05df \u05d4\u05de\u05d9\u05d5\u05d7\u05d3 \u05d4\u05d6\u05d4 \u05e9\u05dc ECD, <strong>\u05d3\"\u05e8 \u05d2'\u05e8\u05d5\u05dd \u05e8\u05d6\u05e0\u05de\u05d4\u05e8\u05d9,<\/strong> \u05e8\u05d5\u05e4\u05d0 \u05dc\u05e8\u05e4\u05d5\u05d0\u05d4 \u05e4\u05e0\u05d9\u05de\u05d9\u05ea \u05d1- <strong>\u05d1\u05d9\u05ea \u05d4\u05d7\u05d5\u05dc\u05d9\u05dd \u05d4\u05d0\u05d5\u05e0\u05d9\u05d1\u05e8\u05e1\u05d9\u05d8\u05d0\u05d9 \u05d1\u05d3\u05d9\u05d6'\u05d5\u05df<\/strong>, \u05d0- <strong>\u05de\u05e8\u05db\u05d6 \u05d4\u05d8\u05d9\u05e4\u05d5\u05dc \u05d1\u05d4\u05e4\u05e0\u05d9\u05d5\u05ea \u05e9\u05dc \u05d4-ECD<\/strong>, \u05de\u05d3\u05d1\u05e8 \u05e2\u05dc <strong>\u05de\u05d7\u05dc\u05ea \u05d0\u05e8\u05d3\u05d4\u05d9\u05d9\u05dd-\u05e6'\u05e1\u05d8\u05e8 (ECD)<\/strong>. \u05d4\u05d5\u05d0 \u05de\u05e1\u05d1\u05d9\u05e8 \u05de\u05d4\u05d5 ECD, \u05de\u05d3\u05d5\u05e2 \u05dc\u05e2\u05d9\u05ea\u05d9\u05dd \u05e7\u05e9\u05d4 \u05dc\u05d0\u05d1\u05d7\u05df \u05d0\u05d5\u05ea\u05d5, \u05d5\u05db\u05d9\u05e6\u05d3 \u05d8\u05d9\u05e4\u05d5\u05dc\u05d9\u05dd \u05de\u05de\u05d5\u05e7\u05d3\u05d9\u05dd \u05d7\u05d3\u05e9\u05d9\u05dd \u05ea\u05d5\u05e8\u05de\u05d9\u05dd \u05dc\u05e9\u05d9\u05e4\u05d5\u05e8 \u05d4\u05ea\u05d5\u05e6\u05d0\u05d5\u05ea \u05d4\u05e7\u05dc\u05d9\u05e0\u05d9\u05d5\u05ea \u05e9\u05dc \u05d4\u05de\u05d8\u05d5\u05e4\u05dc\u05d9\u05dd.<\/p>\n<p><strong>\u05d4\u05e1\u05de\u05d9\u05e0\u05e8 \u05d4\u05de\u05e7\u05d5\u05d5\u05df \u05d4\u05d6\u05d4 \u05de\u05d5\u05e2\u05d1\u05e8 \u05d1\u05e6\u05e8\u05e4\u05ea\u05d9\u05ea<\/strong>.<\/p>\n<p>\u05d1\u05e1\u05e8\u05d8\u05d5\u05df \u05d6\u05d4 \u05de\u05d5\u05e4\u05d9\u05e2\u05d4 \u05d4\u05d5\u05d3\u05e2\u05d4 \u05de\u05d0\u05ea <strong>\u05e4\u05e8\u05d5\u05e4' \u05d6'\u05d5\u05dc\u05d9\u05d0\u05df \u05d4\u05d0\u05e8\u05d5\u05e9,<\/strong> \u05e8\u05d5\u05e4\u05d0 \u05d1\u05db\u05d9\u05e8 \u05d1- <strong>\u05de\u05e8\u05db\u05d6 \u05d4\u05d8\u05d9\u05e4\u05d5\u05dc \u05d1\u05d4\u05e4\u05e0\u05d9\u05d5\u05ea \u05dc-ECD \u05d1\u05d1\u05d9\u05ea \u05d4\u05d7\u05d5\u05dc\u05d9\u05dd \u05e4\u05d9\u05d8\u05d9-\u05e1\u05dc\u05e4\u05d8\u05e8\u05d9\u05d9\u05e8 \u05d1\u05e4\u05e8\u05d9\u05d6, \u05e6\u05e8\u05e4\u05ea<\/strong>. \u05d4\u05d5\u05d0 \u05e2\u05d5\u05de\u05d3 \u05d1\u05e8\u05d0\u05e9 \u05d4\u05de\u05e8\u05db\u05d6 \u05d4\u05e6\u05e8\u05e4\u05ea\u05d9 \u05dc\u05d9\u05d9\u05e2\u05d5\u05e5 \u05d1\u05e0\u05d5\u05e9\u05d0 \u05d4\u05d9\u05e1\u05d8\u05d9\u05d5\u05e6\u05d9\u05d8\u05d5\u05d6\u05d9\u05e1.<\/p>\n<p>\u05d1\u05e1\u05e8\u05d8\u05d5\u05df \u05de\u05d5\u05e6\u05d2 \u05d2\u05dd \u05e1\u05d9\u05e4\u05d5\u05e8 \u05de\u05e8\u05d2\u05e9 \u05e9\u05dc \u05de\u05d8\u05d5\u05e4\u05dc \u05de- <strong>\u05de\u05e8 \u05d6'\u05d0\u05e7 \u05d3\u05d5\u05d8\u05d5,<\/strong> \u05d0\u05e9\u05e8 \u05de\u05e9\u05ea\u05e3 \u05d1\u05d0\u05d5\u05de\u05e5 \u05d0\u05ea \u05de\u05e1\u05e2\u05d5 \u05e2\u05dd ECD, \u05d4\u05d7\u05dc \u05de\u05ea\u05d7\u05d5\u05e9\u05d5\u05ea \u05e9\u05dc \u05db\u05e2\u05e1 \u05d5\u05d1\u05dc\u05d1\u05d5\u05dc \u05d5\u05e2\u05d3 \u05dc\u05ea\u05e7\u05d5\u05d5\u05d4 \u05d5\u05d4\u05e2\u05e6\u05de\u05d4.<\/p>\n<p><strong>\u05ea\u05dc\u05de\u05d3\u05d5:<\/strong><\/p>\n<ul>\n<li>\u05de\u05d4 \u05e9\u05d4\u05d5\u05e4\u05da \u05d0\u05ea \u05d4-ECD \u05dc\u05e1\u05d5\u05d2 \u05e0\u05d3\u05d9\u05e8 \u05d5\u05de\u05d5\u05e8\u05db\u05d1 \u05e9\u05dc \u05e1\u05e8\u05d8\u05df \u05d3\u05dd \u05d3\u05dc\u05e7\u05ea\u05d9<\/li>\n<li>\u05de\u05d3\u05d5\u05e2 \u05e7\u05e9\u05d4 \u05dc\u05d0\u05d1\u05d7\u05df ECD \u05d1\u05e9\u05dc\u05d1 \u05de\u05d5\u05e7\u05d3\u05dd, \u05d5\u05d0\u05d9\u05dc\u05d5 \u05ea\u05e1\u05de\u05d9\u05e0\u05d9\u05dd \u05d9\u05e9 \u05dc\u05e9\u05d9\u05dd \u05dc\u05d1 \u05d0\u05dc\u05d9\u05d4\u05dd<\/li>\n<li>\u05db\u05d9\u05e6\u05d3 \u05de\u05d5\u05d8\u05e6\u05d9\u05d5\u05ea \u05db\u05de\u05d5 <strong>BRAFV600E<\/strong> \u05dc\u05d4\u05e9\u05e4\u05d9\u05e2 \u05e2\u05dc \u05d1\u05d7\u05d9\u05e8\u05ea \u05d4\u05d8\u05d9\u05e4\u05d5\u05dc<\/li>\n<li>\u05db\u05d9\u05e6\u05d3 \u05d8\u05d9\u05e4\u05d5\u05dc\u05d9\u05dd \u05de\u05de\u05d5\u05e7\u05d3\u05d9\u05dd, \u05db\u05d2\u05d5\u05df <strong>BRAF \u05d5-MEK<\/strong> \u05de\u05e2\u05db\u05d1\u05d9\u05dd, \u05de\u05e1\u05d9\u05d9\u05e2\u05d9\u05dd \u05dc\u05d7\u05d5\u05dc\u05d9\u05dd<\/li>\n<li>\u05de\u05d3\u05d5\u05e2 \u05ea\u05de\u05d9\u05db\u05d4 \u05d1\u05d1\u05e8\u05d9\u05d0\u05d5\u05ea \u05d4\u05e0\u05e4\u05e9 \u05d5\u05d0\u05d9\u05db\u05d5\u05ea \u05d4\u05d7\u05d9\u05d9\u05dd \u05d4\u05df \u05d7\u05e9\u05d5\u05d1\u05d5\u05ea<\/li>\n<li>\u05de\u05d3\u05d5\u05e2 \u05d4- <strong>\u05d4\u05d1\u05e8\u05d9\u05ea \u05d4\u05d2\u05dc\u05d5\u05d1\u05dc\u05d9\u05ea \u05e9\u05dc ECD<\/strong> \u05d4\u05d0\u05dd \u05d4\u05d9\u05d0 \u05e7\u05d9\u05d9\u05de\u05ea \u05d5\u05db\u05d9\u05e6\u05d3 \u05d4\u05d9\u05d0 \u05de\u05e1\u05d9\u05d9\u05e2\u05ea \u05dc\u05d7\u05d5\u05dc\u05d9\u05dd \u05d5\u05dc\u05de\u05e9\u05e4\u05d7\u05d5\u05ea \u05d1\u05e8\u05d7\u05d1\u05d9 \u05d4\u05e2\u05d5\u05dc\u05dd<\/li>\n<\/ul>\n<p>\u05e1\u05e8\u05d8\u05d5\u05df \u05d6\u05d4 \u05d4\u05d5\u05d0 \u05d7\u05dc\u05e7 \u05de\u05d4\u05de\u05e9\u05d9\u05de\u05d4 \u05d4\u05de\u05ea\u05de\u05e9\u05db\u05ea \u05e9\u05dc\u05e0\u05d5 \u05dc\u05d4\u05d2\u05d1\u05d9\u05e8 \u05d0\u05ea \u05d4\u05de\u05d5\u05d3\u05e2\u05d5\u05ea, \u05dc\u05d4\u05e6\u05d9\u05e2 \u05ea\u05de\u05d9\u05db\u05d4 \u05d5\u05dc\u05e1\u05d9\u05d9\u05e2 \u05d1\u05e7\u05d9\u05d3\u05d5\u05dd \u05d4\u05de\u05d7\u05e7\u05e8 \u05dc\u05de\u05e2\u05df \u05d0\u05e0\u05e9\u05d9\u05dd \u05d4\u05de\u05d5\u05e9\u05e4\u05e2\u05d9\u05dd \u05de- <strong>\u05de\u05d7\u05dc\u05ea \u05d0\u05e8\u05d3\u05d4\u05d9\u05d9\u05dd-\u05e6'\u05e1\u05d8\u05e8.<\/strong><\/p>","protected":false},"excerpt":{"rendered":"<p>In this special ECD webinar, Dr. Jerome Razanamahery, an internal medicine doctor at Dijon University Hospital, an ECD referral care center, talks about Erdheim-Chester Disease (ECD). He explains what ECD [&hellip;]<\/p>\n","protected":false},"author":20,"featured_media":113542,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","cybocfi_hide_featured_image":"yes","footnotes":"","_links_to":"","_links_to_target":""},"categories":[351],"tags":[5676,5675,5678,387,5317,102,5674,5679,5677,116,4966,5673,4961,4958],"class_list":["post-113541","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-webinar-recordings","tag-braf-inhibitors","tag-brafv600e-mutation","tag-dr-jerome-razanamahery","tag-ecdga","tag-erdheim-chester-disease","tag-histiocytosis","tag-inflammatory-myeloid-neoplasm","tag-julien-haroche","tag-mek-inhibitors","tag-patient-support","tag-rare-blood-cancer","tag-rare-disease-awareness","tag-rare-disease-research","tag-targeted-therapy"],"_links":{"self":[{"href":"https:\/\/www.erdheim-chester.org\/he\/wp-json\/wp\/v2\/posts\/113541","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.erdheim-chester.org\/he\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.erdheim-chester.org\/he\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/he\/wp-json\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/he\/wp-json\/wp\/v2\/comments?post=113541"}],"version-history":[{"count":0,"href":"https:\/\/www.erdheim-chester.org\/he\/wp-json\/wp\/v2\/posts\/113541\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/he\/wp-json\/wp\/v2\/media\/113542"}],"wp:attachment":[{"href":"https:\/\/www.erdheim-chester.org\/he\/wp-json\/wp\/v2\/media?parent=113541"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/he\/wp-json\/wp\/v2\/categories?post=113541"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/he\/wp-json\/wp\/v2\/tags?post=113541"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}