{"id":66233,"date":"2019-12-30T23:55:42","date_gmt":"2019-12-31T04:55:42","guid":{"rendered":"https:\/\/www.erdheim-chester.org\/%ce%bf-fda-%cf%87%ce%bf%cf%81%ce%ae%ce%b3%ce%b7%cf%83%ce%b5-breakthrough-designation\/"},"modified":"2019-12-30T23:55:42","modified_gmt":"2019-12-31T04:55:42","slug":"%ce%bf-fda-%cf%87%ce%bf%cf%81%ce%ae%ce%b3%ce%b7%cf%83%ce%b5-breakthrough-designation","status":"publish","type":"post","link":"https:\/\/www.erdheim-chester.org\/el\/%ce%bf-fda-%cf%87%ce%bf%cf%81%ce%ae%ce%b3%ce%b7%cf%83%ce%b5-breakthrough-designation\/","title":{"rendered":"\u039f FDA \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b5 Breakthrough Designation"},"content":{"rendered":"<p>\u039f \u0391\u03bc\u03b5\u03c1\u03b9\u03ba\u03b1\u03bd\u03b9\u03ba\u03cc\u03c2 \u039f\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03a4\u03c1\u03bf\u03c6\u03af\u03bc\u03c9\u03bd \u03ba\u03b1\u03b9 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b5 \u03c4\u03bf\u03bd \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03bc\u03cc Breakthrough Therapy Designation \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03bc\u03c0\u03b9\u03bc\u03b5\u03c4\u03b9\u03bd\u03af\u03bc\u03c0\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 \u03b9\u03c3\u03c4\u03b9\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ac \u03bd\u03b5\u03bf\u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03b1 (Erdheim-Chester \u039d\u03cc\u03c3\u03bf\u03c2, Rosai-Dorfman, \u0399\u03c3\u03c4\u03b9\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03c3\u03b7 Langerhans), \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03bf\u03b9 \u03b4\u03b5\u03bd \u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03c4\u03b7 \u03bc\u03b5\u03c4\u03ac\u03bb\u03bb\u03b1\u03be\u03b7 <em>BRAF<\/em> V600. \u0391\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03ad\u03bd\u03b1 \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf \u03b2\u03ae\u03bc\u03b1 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03b1 \u03b5\u03bc\u03c0\u03c1\u03cc\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 <em>\u03bc\u03b5 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc BRAF<\/em> ECD, \u03b1\u03bb\u03bb\u03ac \u03b3\u03b9\u03b1 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03b9\u03c3\u03c4\u03b9\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03c3\u03b7. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u039f \u0391\u03bc\u03b5\u03c1\u03b9\u03ba\u03b1\u03bd\u03b9\u03ba\u03cc\u03c2 \u039f\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03a4\u03c1\u03bf\u03c6\u03af\u03bc\u03c9\u03bd \u03ba\u03b1\u03b9 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b5 \u03c4\u03bf\u03bd \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03bc\u03cc Breakthrough Therapy Designation \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03bc\u03c0\u03b9\u03bc\u03b5\u03c4\u03b9\u03bd\u03af\u03bc\u03c0\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 \u03b9\u03c3\u03c4\u03b9\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ac \u03bd\u03b5\u03bf\u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03b1 (Erdheim-Chester \u039d\u03cc\u03c3\u03bf\u03c2, Rosai-Dorfman, \u0399\u03c3\u03c4\u03b9\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03c3\u03b7 Langerhans), \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03bf\u03b9 \u03b4\u03b5\u03bd \u03c6\u03ad\u03c1\u03bf\u03c5\u03bd [&hellip;]<\/p>\n","protected":false},"author":20,"featured_media":91085,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","_wds_title":"","_wds_metadesc":"","_wds_focus-keywords":"","_wds_meta-robots-adv":"","_wds_meta-robots-noindex":false,"_wds_meta-robots-nofollow":false,"_wds_meta-robots-index":false,"_wds_meta-robots-follow":false,"_wds_autolinks-exclude":false,"_wds_canonical":"","_wds_redirect":"","_wds_opengraph":[],"_wds_twitter":[],"cybocfi_hide_featured_image":"","wds_primary_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2080],"tags":[2124],"class_list":["post-66233","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-2080","tag-2019-el"],"_links":{"self":[{"href":"https:\/\/www.erdheim-chester.org\/el\/wp-json\/wp\/v2\/posts\/66233","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.erdheim-chester.org\/el\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.erdheim-chester.org\/el\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/el\/wp-json\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/el\/wp-json\/wp\/v2\/comments?post=66233"}],"version-history":[{"count":0,"href":"https:\/\/www.erdheim-chester.org\/el\/wp-json\/wp\/v2\/posts\/66233\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/el\/wp-json\/wp\/v2\/media\/91085"}],"wp:attachment":[{"href":"https:\/\/www.erdheim-chester.org\/el\/wp-json\/wp\/v2\/media?parent=66233"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/el\/wp-json\/wp\/v2\/categories?post=66233"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.erdheim-chester.org\/el\/wp-json\/wp\/v2\/tags?post=66233"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}